Target Name: LPAR6
NCBI ID: G10161
Review Report on LPAR6 Target / Biomarker Content of Review Report on LPAR6 Target / Biomarker
LPAR6
Other Name(s): P2Y5 | lysophosphatidic acid receptor 6 | purinergic receptor P2Y G protein-coupled protein 5 | LPAR6 variant 1 | HYPT8 | ARWH1 | Oleoyl-L-alpha-lysophosphatidic acid receptor | P2RY5 | RB intron encoded G-protein coupled receptor | Lysophosphatidic acid receptor 6 | LAH3 | Lysophosphatidic acid receptor 6, transcript variant 1 | LPA receptor 6 | purinergic receptor 5 | P2Y purinoceptor 5 | oleoyl-L-alpha-lysophosphatidic acid receptor | purinergic receptor P2Y, G-protein coupled, 5 | LPA-6 | OTTHUMP00000018396 | MGC120358 | Purinergic receptor 5 | G-protein coupled purinergic receptor P2Y5 | LPAR6_HUMAN

LPAR6: A Potential Drug Target and Biomarker

Lipid-binding protein-6 (LPAR6) is a protein that is expressed in various tissues throughout the body, including the liver, muscle, and heart. It is a 22-kDa protein that is characterized by its ability to bind to lipids, such as triacylglycerols, which are found in animal fats and cell membranes. In recent years, researchers have become increasingly interested inLPAR6 as a potential drug target and biomarker due to its unique structure and various functions in the body.

LPAR6 functions as a negative regulator of lipid metabolism byLCP-LCP signaling pathway. It plays a crucial role in the regulation of lipid metabolism byLCP-LCP signaling pathway. This pathway is involved in the production and degradation of lipids in the body, and it is known to play a key role in the development and progression of various diseases, such as obesity, diabetes, and cardiovascular disease.

Research has shown that changes in the levels of LPAR6 can have a significant impact on lipid metabolism and overall health. For example, studies have shown that individuals with low LPAR6 levels are more likely to be overweight or obese, and they may also be at a higher risk for developing certain diseases, such as cardiovascular disease and diabetes. Additionally, individuals with high LPAR6 levels may have a lower risk of disease and be at a healthy weight.

In addition to its role in lipid metabolism, LPAR6 has also been shown to play a key role in the regulation of cellular signaling pathways. It is a known regulator of the PI3K/Akt signaling pathway, which is involved in the production and degradation of phospholipids. Additionally, LPAR6 has also been shown to regulate the NF-kappa-B signaling pathway, which is involved in inflammation and stress responses.

As a potential drug target, LPAR6 has the potential to be used for the treatment of various diseases that are related to lipid metabolism or cellular signaling pathways. For example, individuals with high LPAR6 levels may be at a lower risk of developing cardiovascular disease, and therefore, may be a good candidate for a drug that targetsLPAR6 to prevent or reverse the development of cardiovascular disease. Additionally, individuals with low LPAR6 levels may be at a higher risk of developing certain diseases, such as obesity or diabetes, and a drug that targetsLPAR6 may have the potential to reverse these conditions.

In conclusion, LPAR6 is a protein that has the potential to be a drug target and biomarker due to its unique structure and various functions in the body. Its role in the regulation of lipid metabolism and cellular signaling pathways makes it an attractive candidate for drug development. Further research is needed to fully understand the potential benefits and risks of a drug that targets LPAR6, and to develop safe and effective treatments for various diseases associated with this protein.

Protein Name: Lysophosphatidic Acid Receptor 6

Functions: Binds to oleoyl-L-alpha-lysophosphatidic acid (LPA). Intracellular cAMP is involved in the receptor activation. Important for the maintenance of hair growth and texture

The "LPAR6 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LPAR6 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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