SAMD1: A Protein with A Wide Range of Functions (G90378)

Target Name: SAMD1

NCBI ID: G90378

SAMD1

SAMD1: A Protein with A Wide Range of Functions

SAMD1, also known as sterile alpha motif domain-containing protein 1, is a protein that is expressed in a variety of tissues throughout the body. It is characterized by a unique protein domain that consists of a sterile alpha motif, which is a specific type of domain that is found in many proteins that are involved in various cellular processes.

The sterile alpha motif is a short sequence of amino acids that is composed of four amino acids: alanine, glutamic acid, aspartic acid, and glycine. The alpha motif is a specific type of domain that is characterized by the presence of a specific type of secondary structure, which is a pattern of arrangement of atoms in a molecule. In the case of SAMD1, the alpha motif is responsible for the unique structural features of the protein that give it its unique structure and function.

One of the key functions of SAMD1 is its role in the regulation of various cellular processes that are involved in the development and maintenance of tissues. For example, SAMD1 is involved in the regulation of cell growth, cell differentiation, and cell cycle progression. It is also involved in the regulation of cell signaling pathways, as well as in the regulation of various cellular processes that are involved in the development and maintenance of tissues.

In addition to its role in cellular regulation, SAMD1 is also a potential drug target and biomarker. The alpha motif is a unique structural feature that is found in many proteins, and as a result, targeting this domain may be a useful way to target proteins that are involved in various cellular processes. Additionally, the sterile alpha motif is also a potential biomarker for certain diseases, as the presence of this domain may be associated with the development of certain diseases.

Another potential function of SAMD1 is its role in the regulation of inflammation. SAMD1 is involved in the regulation of various cellular processes that are involved in the immune response, and as a result, it may be a potential target for drugs that are used to treat inflammatory diseases.

Overall, SAMD1 is a protein that has a wide range of functions in various cellular processes that are important for the development and maintenance of tissues. Its unique alpha motif domain, as well as its involvement in the regulation of various cellular processes, make it a potential drug target and biomarker. Further research is needed to fully understand the role of SAMD1 in these processes and to develop effective treatments for diseases that are caused by SAMD1 dysfunction.

Protein Name: Sterile Alpha Motif Domain Containing 1

Functions: Unmethylated CpG islands (CGIs)-binding protein which localizes to H3K4me3-decorated CGIs, where it acts as a transcriptional repressor (PubMed:33980486). Tethers L3MBTL3 to chromatin and interacts with the KDM1A histone demethylase complex to modulate H3K4me2 and H3K4me3 levels at CGIs (PubMed:33980486). Plays a role in atherogenesis by binding with LDL on cell surface and promoting LDL oxidation which leads to the formation of foam cell (PubMed:16159594, PubMed:34006929)

The "SAMD1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SAMD1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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