Target Name: LRRFIP1
NCBI ID: G9208
Review Report on LRRFIP1 Target / Biomarker Content of Review Report on LRRFIP1 Target / Biomarker
LRRFIP1
Other Name(s): GCF-2 | FLIIAP1 | GC-binding factor 2 | LRRFIP1 variant 1 | NEDD8-conjugating enzyme | FLAP1 | Leucine-rich repeat flightless-interacting protein 1 (isoform 5) | HUFI-1 | MGC119738 | Leucine rich repeat (In FLII) interacting protein 1 | LRR binding FLII interacting protein 1, transcript variant 3 | TRIP | OTTHUMP00000164477 | leucine rich repeat (in FLII) interacting protein 1 | Leucine rich repeat (in FLII) interacting protein 1 | Leucine-rich repeat flightless-interacting protein 1 (isoform 1) | OTTHUMP00000164478 | OTTHUMP00000196808 | LRRF1_HUMAN | LRRFIP1 variant 5 | FLAP-1 | LRR binding FLII interacting protein 1 | LRR FLII-interacting protein 1 | MGC10947 | MGC119739 | LRR binding FLII interacting protein 1, transcript variant 5 | LRRFIP1 variant 3 | Leucine-rich repeat flightless-interacting protein 1 (isoform 3) | LRR binding FLII interacting protein 1, transcript variant 1 | GCF2 | OTTHUMP00000196809 | TAR RNA-interacting protein | Leucine-rich repeat flightless-interacting protein 1

LRRFIP1 as A Potential Drug Target and Biomarker

LRRFIP1 (long non-coding RNA) is a molecule that has been identified as a potential drug target (also known as biomarker) for the treatment of various diseases, including cancer. LRRFIP1 is a gene that encodes a protein that is expressed in various tissues and cells of the body. The protein produced by this gene has been shown to play a role in the development and progression of several diseases, including cancer.

Disease and Cancer

LRRFIP1 has been shown to be involved in the development and progression of various diseases, including cancer. For example, studies have shown that LRRFIP1 is overexpressed in various types of cancer, including breast, ovarian, and prostate cancer. This overexpression is thought to contribute to the development and progression of these diseases.

In addition to its role in cancer, LRRFIP1 has also been shown to be involved in the development and progression of other diseases. For example, studies have shown that LRRFIP1 is overexpressed in individuals with heart disease, and that this overexpression is associated with an increased risk of heart failure. LRRFIP1 has also been shown to be involved in the development and progression of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

Targeting LRRFIP1

The potential drug target for LRRFIP1 is based on its role in the development and progression of various diseases. LRRFIP1 has been shown to play a role in the development and progression of cancer, heart disease, and neurodegenerative diseases. Therefore, LRRFIP1 could be a potential drug target for these diseases.

One approach to targeting LRRFIP1 is to use small molecules to inhibit its expression. These small molecules could be used to prevent LRRFIP1 from being translated into the protein that it encodes. Alternatively, small molecules could be used to activate LRRFIP1, causing it to be degraded.

Another approach to targeting LRRFIP1 is to use antibodies to block its function. These antibodies could be used to specifically bind to LRRFIP1, preventing it from interacting with its downstream targets. This could result in the inhibition of LRRFIP1's activity.

LRRFIP1 as a Biomarker

LRRFIP1 has also been shown to be a potential biomarker for the treatment of various diseases, including cancer. This is because the expression of LRRFIP1 is often affected by the presence of certain diseases, and therefore its expression can provide information about the presence and progression of these diseases.

For example, LRRFIP1 has been shown to be overexpressed in individuals with cancer, and this overexpression is often associated with the development and progression of these diseases. Therefore, the expression of LRRFIP1 can be used as a biomarker for the presence and progression of cancer.

LRRFIP1 has also been shown to be overexpressed in individuals with heart disease, and this overexpression is associated with an increased risk of heart failure. Therefore, the expression of LRRFIP1 can also be used as a biomarker for the presence and progression of heart disease.

Conclusion

LRRFIP1 is a molecule that has been shown to play a role in the development and progression of various diseases, including cancer. Its expression is often affected by the presence of certain diseases, and therefore it has the potential to be used as a biomarker for the diagnosis and treatment of these diseases. Further research is needed to fully understand the role of LRRFIP1 as a drug target and biomarker, and to develop effective treatments for the treatment of these diseases.

Protein Name: LRR Binding FLII Interacting Protein 1

Functions: Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding

The "LRRFIP1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LRRFIP1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

LRRFIP1P1 | LRRFIP2 | LRRIQ1 | LRRIQ3 | LRRIQ4 | LRRK1 | LRRK2 | LRRN1 | LRRN2 | LRRN3 | LRRN4 | LRRN4CL | LRRTM1 | LRRTM2 | LRRTM3 | LRRTM4 | LRSAM1 | LRTM1 | LRTM2 | LRTOMT | LRWD1 | LSAMP | LSG1 | LSINCT5 | LSm Protein Complex | LSM1 | Lsm1-7 complex | LSM10 | LSM11 | LSM12 | LSM14A | LSM14B | LSM2 | LSM3 | LSM4 | LSM5 | LSM6 | LSM7 | LSM8 | LSMEM1 | LSMEM2 | LSP1 | LSP1P2 | LSP1P3 | LSP1P4 | LSP1P5 | LSR | LSS | LST1 | LTA | LTA4H | LTB | LTB4R | LTB4R2 | LTBP1 | LTBP2 | LTBP3 | LTBP4 | LTBR | LTC4S | LTF | LTK | LTN1 | LTO1 | LTV1 | LUADT1 | LUC7L | LUC7L2 | LUC7L3 | LUCAT1 | LUM | LUNAR1 | LURAP1 | LURAP1L | LURAP1L-AS1 | Luteinizing hormone | LUZP1 | LUZP2 | LUZP4 | LUZP6 | LVRN | LXN | LY6D | LY6E | LY6E-DT | LY6G5B | LY6G5C | LY6G6C | LY6G6D | LY6G6E | LY6G6F | LY6H | LY6K | LY75 | LY75-CD302 | LY86 | LY86-AS1 | LY9 | LY96 | LYAR