Target Name: MS4A1
NCBI ID: G931
Review Report on MS4A1 Target / Biomarker Content of Review Report on MS4A1 Target / Biomarker
MS4A1
Other Name(s): S7 | FMC7 | B1 | B-lymphocyte cell-surface antigen B1 | MS4A1 variant 1 | Leukocyte surface antigen Leu-16 | membrane-spanning 4-domains, subfamily A, member 1 | B-lymphocyte surface antigen B1 | B-lymphocyte antigen CD20 | Bp35 | MS4A2 | CD20 | LEU-16 | CVID5 | CD20_HUMAN | CD20 antigen | CD20 receptor | membrane spanning 4-domains A1 | leukocyte surface antigen Leu-16 | Membrane spanning 4-domains A1, transcript variant 1 | Membrane-spanning 4-domains subfamily A member 1

MS4A1: A Potential Drug Target and Biomarker for Various Diseases

MS4A1 (Mesothelin-Specific Antigen 1) is a protein that is expressed in various tissues and cells in the body. It is a glycoprotein with a molecular weight of approximately 120 kDa and a monomeric structure. MS4A1 is involved in cell signaling, tissue structure, and wound healing. It is a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

The protein encoded by the MS4A1 gene is a member of the heparan sulfate proteoglycan (HSPG) family. HSPG proteins are involved in various cellular processes, including cell signaling, adhesion, and tissue structure. The HSPG protein family has over 20 different isoforms, including MS4A1, which is expressed in various tissues and cells in the body.

MS4A1 is involved in cell signaling and tissue structure. It is a critical regulator of cell adhesion and migration. MS4A1 plays a role in the development and maintenance of tight junctions, which are specialized cell-cell junctions that mediate intercellular communication. tight junctions are involved in various physiological processes, including cell signaling, ion and solute transport, and embryonic development.

MS4A1 is also involved in tissue structure and wound healing. It is a key regulator of the extracellular matrix (ECM) during the wound healing process. ECM is a complex structure that is involved in the regulation of various physiological processes, including cell signaling, migration, and invasion. The ECM provides mechanical tension to maintain the integrity of tissues and helps to promote wound healing.

MS4A1 is a potential drug target and biomarker for various diseases. Its involvement in cell signaling, tissue structure, and wound healing makes it an attractive target for small molecule inhibitors. Many studies have identified potential small molecule inhibitors that can inhibit MS4A1 function. These inhibitors have been shown to have various biological effects, including the inhibition of cell migration, the regulation of cell adhesion, and the promotion of wound healing.

In addition to its potential as a drug target, MS4A1 is also a potential biomarker for various diseases. Its involvement in cell signaling and tissue structure makes it an attractive target for diagnostic tests. Many studies have shown that changes in MS4A1 expression levels can be associated with various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. The detection of changes in MS4A1 expression levels may provide a valuable diagnostic tool for these diseases.

In conclusion, MS4A1 is a protein that is involved in various cellular processes in the body. Its involvement in cell signaling, tissue structure, and wound healing makes it a potential drug target and biomarker for various diseases. The identification of potential small molecule inhibitors and diagnostic tests for MS4A1 is an exciting area of research that has the potential to lead to new treatments and therapies for a variety of diseases.

Protein Name: Membrane Spanning 4-domains A1

Functions: B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes (PubMed:3925015, PubMed:7684739, PubMed:12920111). Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR (PubMed:7684739, PubMed:12920111, PubMed:18474602)

The "MS4A1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MS4A1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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MS4A10 | MS4A12 | MS4A13 | MS4A14 | MS4A15 | MS4A18 | MS4A2 | MS4A3 | MS4A4A | MS4A4E | MS4A5 | MS4A6A | MS4A6E | MS4A7 | MS4A8 | MSANTD1 | MSANTD2 | MSANTD3 | MSANTD4 | MSC | MSC-AS1 | MSGN1 | MSH2 | MSH3 | MSH4 | MSH5 | MSH5-SAPCD1 | MSH6 | MSI1 | MSI2 | MSL1 | MSL2 | MSL3 | MSL3P1 | MSLN | MSLNL | MSMB | MSMO1 | MSMP | MSN | MSNP1 | MSR1 | MSRA | MSRA-DT | MSRB1 | MSRB1P1 | MSRB2 | MSRB3 | MSRB3-AS1 | MSS51 | MST1 | MST1L | MST1P2 | MST1R | MSTN | MSTO1 | MSTO2P | MSX1 | MSX2 | MSX2P1 | MT1A | MT1B | MT1DP | MT1E | MT1F | MT1G | MT1H | MT1HL1 | MT1IP | MT1JP | MT1L | MT1M | MT1P1 | MT1P3 | MT1X | MT1XP1 | MT2A | MT3 | MT4 | MTA1 | MTA1-DT | MTA2 | MTA3 | MTAP | MTARC1 | MTARC2 | MTATP6P1 | MTATP8P1 | MTBP | MTCH1 | MTCH2 | MTCL1 | MTCO1P1 | MTCO1P12 | MTCO1P15 | MTCO2P33 | MTCO3P1 | MTCO3P12 | MTCP1 | MTDH