Understanding ADIPOQ: A Potential Drug Target for Obesity (G9370)

Target Name: ADIPOQ

NCBI ID: G9370

ADIPOQ

Understanding ADIPOQ: A Potential Drug Target for Obesity

Adipose Most Abundant Gene Transcript 1 (ADIPOQ) is a protein that is expressed in high levels in adipose tissue, which is a type of tissue that is found throughout the body, including fat cells, blood vessels, and surrounding cells. ADIPOQ has been identified as a potential drug target and has been shown to play a role in a number of biological processes that are related to obesity and related health conditions.

The ADIPOQ gene is located on chromosome 12q13 and encodes a protein that is composed of 156 amino acids. The protein has a molecular weight of 19.1 kDa and a pre-membrane glycylation of 2.9 kDa. ADIPOQ is expressed in a variety of tissues and cells in the body, including adipose tissue, muscle tissue, blood vessels, and the brain.

One of the key functions of ADIPOQ is its role in the regulation of lipid metabolism. Adipose tissue is a major source of energy and adiposity is associated with a number of health problems, including obesity, type 2 diabetes, and cardiovascular disease. ADIPOQ has been shown to play a role in the regulation of lipid metabolism by promoting the storage of lipids in adipose tissue and inhibiting the breakdown of lipids in muscle tissue.

In addition to its role in lipid metabolism, ADIPOQ is also involved in a number of other biological processes that are related to obesity and related health conditions. For example, ADIPOQ has been shown to play a role in the regulation of nutrient uptake and storage, as well as in the regulation of cellular signaling pathways that are involved in the development and maintenance of obesity.

ADIPOQ is also a potential biomarker for the diagnosis and treatment of obesity and related health conditions. The administration of AdipoQ to obese rats has been shown to result in a reduction in body weight and a decrease in the levels of certain genes that are involved in the development of obesity. In addition, the levels of ADIPOQ have been shown to be associated with an increase in the risk of certain health problems, such as cardiovascular disease and type 2 diabetes.

Despite the potential benefits of ADIPOQ as a drug target and biomarker, much more research is needed to fully understand its role in the regulation of obesity and related health conditions. For example, it is not clear what the most effective way to administer ADIPOQ to humans, or what the optimal levels of ADIPOQ are for use as a drug. Additionally, further research is needed to determine the exact mechanisms by which ADIPOQ promotes the storage of lipids in adipose tissue and inhibits the breakdown of lipids in muscle tissue.

In conclusion, ADIPOQ is a protein that is expressed in high levels in adipose tissue and has been shown to play a role in a number of biological processes that are related to obesity and related health conditions. As a potential drug target and biomarker, ADIPOQ is a promising target for the development of new treatments for obesity and related health conditions. Further research is needed to fully understand its role in the regulation of lipid metabolism and its potential as a drug.

Protein Name: Adiponectin, C1Q And Collagen Domain Containing

Functions: Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW

The "ADIPOQ Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ADIPOQ comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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