Target Name: TATDN2
NCBI ID: G9797
Review Report on TATDN2 Target / Biomarker Content of Review Report on TATDN2 Target / Biomarker
TATDN2
Other Name(s): TATD2_HUMAN | KIAA0218 | TatD DNase domain containing 2 | Putative deoxyribonuclease TATDN2

TATDN2: A Key Regulator of TATA-Element-Dependent Gene Expression

TATDN2 (TATA-associated protein 2) is a protein that is expressed in various tissues of the human body. It is a key regulator of the TATA-element dependent gene expression, which is a widely recognized mechanism of gene regulation in eukaryotic cells. TATA -element is a core element of the TATA-repeating unit, which is a common feature of gene promoters. The TATA-element is responsible for the regulation of gene expression, and TATDN2 is a known regulator of TATA-element-dependent gene expression.

TATDN2 is a 24.8 kDa protein that is expressed in various tissues of the human body, including muscle, heart, kidney, liver, and brain. It is highly conserved, with a calculated pI of 6.9 and a predicted localization in the cytoplasm. TATDN2 is a monomer and has a linear molecular weight of 10.1 kDa. It has a single transmembrane domain and a N-terminus that is involved in protein-protein interactions.

TATDN2 is a key regulator of TATA-element-dependent gene expression. TATA-element is a core element of the TATA-repeating unit, which is a common feature of gene promoters. The TATA-element is responsible for the regulation of gene expression, and TATDN2 is a known regulator of TATA-element-dependent gene expression. TATDN2 has been shown to interact with various TATA-element-containing proteins, including DNA-binding proteins such as histone-modifying enzymes and histone-remodeling enzymes.

TATDN2 is also involved in the regulation of alternative splicing (AS). Alternative splicing is a process by which the cell removes non-coding exons from the pre-mRNA and uses the remaining exons to generate a functional RNA molecule. TATDN2 has been shown to play a role in the regulation of AS by interacting with the protein SIRP1. SIRP1 is a splicing machinery component that is involved in the regulation of AS.

TATDN2 is also involved in the regulation of cell growth and metabolism. It has been shown to play a role in the regulation of cell cycle progression, cell migration, and cell survival. TATDN2 has been shown to interact with various cell-cycle-related proteins , including the cyclin D1 protein.

TATDN2 is also involved in the regulation of inflammation. It has been shown to play a role in the regulation of immune and inflammatory responses. TATDN2 has been shown to interact with various immune-related proteins, including the transcription factor NF-kappa-B.

TATDN2 is also involved in the regulation of cellular signaling pathways. It has been shown to play a role in the regulation of various cellular signaling pathways, including the regulation of cell adhesion, the regulation of cell-cell signaling, and the regulation of intracellular signaling pathways. TATDN2 has been shown to interact with various signaling proteins, including the protein kinase PDK4.

TATDN2 is a potential drug target and has been shown to be involved in various cellular processes that are important for human health and disease. It is involved in the regulation of TATA-element-dependent gene expression, which is a common feature of gene promoters. TATDN2 is also involved in the regulation of alternative splicing, cell growth and metabolism, inflammation, and cellular signaling pathways.

In conclusion, TATDN2 is a protein that is involved in various cellular processes that are important for human health and disease. It is a key regulator of TATA-element-dependent gene expression and has been shown to interact with various proteins involved in

Protein Name: TatD DNase Domain Containing 2

Functions: Putative deoxyribonuclease

The "TATDN2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TATDN2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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