ARPC5: A Potential Drug Target and Biomarker (G10092)

Target Name: ARPC5

NCBI ID: G10092

ARPC5

ARPC5: A Potential Drug Target and Biomarker

Autophagy is a critical intracellular process that regulates cell survival and metabolism. It is a process in which cells break down and recycle damaged or unnecessary cellular components, thereby maintaining cellular homeostasis. Autophagy is regulated by a complex network of genes, including the TOR signaling pathway. One of the key components of the TOR signaling pathway is the protein ARPC5. In this article, we will discuss ARPC5 as a potential drug target and biomarker.

ARPC5: Structure and Function

ARPC5 is a protein that belongs to the ARPC family of proteins. The ARPC family is a conserved group of proteins that are involved in various cellular processes, including cell signaling, cell adhesion, and cytoskeletal organization. ARPC5 is a 21-kDa protein that is expressed in various tissues and cells, including muscle, heart, and brain.

ARPC5 functions as a critical regulator of autophagy. It is involved in the formation of autophagosomes, which are the intracellular organelles that break down damaged or unnecessary cellular components. ARPC5 is also involved in the degradation of autophagosomes, which is critical for maintaining cellular homeostasis.

Mutations in ARPC5 have been linked to various diseases, including cancer, neurodegenerative diseases, and metabolic disorders. Therefore, targeting ARPC5 as a drug target or biomarker has great potential.

Drug Target Potential

ARPC5 is a potential drug target due to its involvement in autophagy regulation. Autophagy is a critical process that helps cells remove damaged or unnecessary cellular components. Therefore, inhibiting autophagy could be a promising strategy for treating various diseases.

ARPC5 is a protein that is involved in the formation and degradation of autophagosomes, which are the intracellular organelles that break down damaged or unnecessary cellular components. Therefore, inhibiting ARPC5 activity could be a promising strategy for treating various diseases.

Biomarker Potential

ARPC5 is also a potential biomarker for various diseases. The deregulation of ARPC5 has been linked to various diseases, including cancer, neurodegenerative diseases, and metabolic disorders. Therefore, measuring the expression of ARPC5 could be a useful diagnostic tool and a potential biomarker for various diseases.

ARPC5 is involved in the formation and degradation of autophagosomes, which are the intracellular organelles that break down damaged or unnecessary cellular components. Therefore, measuring the levels of autophagosomes in various tissues and cells could be a potential biomarker for neurodegenerative diseases.

Conclusion

In conclusion, ARPC5 is a protein that is involved in various cellular processes, including autophagy regulation. Its deregulation has been linked to various diseases, including cancer, neurodegenerative diseases, and metabolic disorders. Therefore, targeting ARPC5 as a drug target or biomarker has great potential.

Targeting ARPC5 as a drug target could be a promising strategy for treating various diseases. Additionally, measuring the expression of ARPC5 could be a useful diagnostic tool and a potential biomarker for various diseases. Further research is needed to fully understand the role of ARPC5 in cellular processes and its potential as a drug target and biomarker.

Protein Name: Actin Related Protein 2/3 Complex Subunit 5

Functions: Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed:29925947)

The "ARPC5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ARPC5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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