SEMA4B: A Transmembrane Protein Potential Drug Target in Neurology

Target Name: SEMA4B

NCBI ID: G10509

SEMA4B

SEMA4B: A Transmembrane Protein Potential Drug Target in Neurology

SEMA4B (semaphorin-C) is a protein that is expressed in various tissues throughout the body, including the brain, lungs, heart, kidneys, and intestines. It is a type of transmembrane protein that consists of four transmembrane domains and a cytoplasmic tail. SEMA4B is known for its role in the regulation of intracellular signaling pathways, including the NF-kappa pathway.

SEMA4B is a protein that has been identified as a potential drug target in the field of neurology. Studies have shown that SEMA4B is involved in the regulation of neurotransmitter release from neurons, which is important for the function of the brain. Additionally, SEMA4B has been shown to play a role in the regulation of pain perception and the modulation of pain modalities.

SEMA4B is also known as sephorin-C, which is a type of transmembrane protein that is characterized by the presence of a heparan sulfate proteoglycan (HSPG) domain on its cytoplasmic tail. HSPG domains are known for their ability to interact with various proteins and to play a role in the regulation of cellular signaling pathways.

SEMA4B is expressed in a variety of tissues throughout the body, including the brain, lungs, heart, kidneys, and intestines. It is a type of transmembrane protein that consists of four transmembrane domains and a cytoplasmic tail. SEMA4B is known for its role in the regulation of intracellular signaling pathways, including the NF-kappa pathway.

SEMA4B has been shown to play a role in the regulation of neurotransmitter release from neurons, which is important for the function of the brain. Studies have shown that SEMA4B is involved in the regulation of the release of dopamine, serotonin, and other neurotransmitters. Additionally, SEMA4B has been shown to play a role in the regulation of pain perception and the modulation of pain modalities.

SEMA4B is also known as sephorin-C, which is a type of transmembrane protein that is characterized by the presence of a heparan sulfate proteoglycan (HSPG) domain on its cytoplasmic tail. HSPG domains are known for their ability to interact with various proteins and to play a role in the regulation of cellular signaling pathways.

In conclusion, SEMA4B is a protein that has been identified as a potential drug target in the field of neurology. Studies have shown that SEMA4B is involved in the regulation of neurotransmitter release from neurons and in the regulation of pain perception and the modulation of pain modalities. Further research is needed to fully understand the role of SEMA4B in these processes and to determine its potential as a drug target.

Protein Name: Semaphorin 4B

Functions: Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons

The "SEMA4B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SEMA4B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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