Target Name: LOC100132077
NCBI ID: G100132077
Review Report on LOC100132077 Target / Biomarker Content of Review Report on LOC100132077 Target / Biomarker
LOC100132077
Other Name(s): Uncharacterized LOC100132077 | uncharacterized LOC100132077

LOC100132077: A Drug Target / Disease Biomarker

LOC100132077 is a protein that is expressed in various tissues of the body, including the brain, heart, kidneys, and liver. It is a member of the LOC1001 family of proteins, which are known for their role in intracellular signaling. LOC100132077 has been identified as a potential drug target or biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

The LOC1001 family of proteins is characterized by the presence of a single transmembrane domain and a cytoplasmic tail. The transmembrane domain is involved in the protein's localization and interactions with other cellular components, while the cytoplasmic tail is involved in the regulation of protein stability and localization to the cell membrane.

LOC100132077 is a 21-kDa protein that is expressed in the brain, heart, kidneys, and liver. It is highly conserved between different species, with the highest sequence identity between human and mouse LOC100132077 proteins. LOC100132077 is predominantly localized to the cytoplasm of cells, with a minor exception in the brain.

In addition to its expression in the brain, LOC100132077 has been shown to be involved in various physiological processes in the body. For example, LOC100132077 has been shown to be involved in the regulation of cell adhesion, migration, and invasion. It has also been shown to play a role in the regulation of ion channels, including the Na+/K+-ATPase.

In addition to its role in intracellular signaling, LOC100132077 has also been identified as a potential drug target or biomarker for various diseases. For example, LOC100132077 has been shown to be overexpressed in various cancer tissues, including breast, ovarian, and colorectal cancer. This suggests that LOC100132077 may be a useful target for cancer therapies.

In addition to its potential as a cancer therapeutic, LOC100132077 has also been identified as a potential biomarker for neurodegenerative diseases. For example, LOC100132077 has been shown to be reduced in the brains of individuals with Alzheimer's disease, a neurodegenerative disease. This suggests that LOC100132077 may be a useful biomarker for the diagnosis and progression of neurodegenerative diseases.

LOC100132077 has also been shown to be involved in the regulation of inflammation and immune response. For example, LOC100132077 has been shown to be involved in the regulation of T cell function and the production of antibodies. This suggests that LOC100132077 may be a useful target for the treatment of autoimmune disorders.

In conclusion, LOC100132077 is a protein that has been identified as a potential drug target or biomarker for various diseases. Its conserved structure and subcellular localization suggest that it may be a good candidate for a variety of therapies, including cancer, neurodegenerative diseases, and autoimmune disorders. Further research is needed to determine the full extent of LOC100132077's potential as a drug target or biomarker.

Protein Name: Uncharacterized LOC100132077

The "LOC100132077 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC100132077 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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