A Promising Drug Target: YKT6 (Synaptobrevin Homolog YKT6) (G10652)

Target Name: YKT6

NCBI ID: G10652

YKT6

A Promising Drug Target: YKT6 (Synaptobrevin Homolog YKT6)

YKT6 (Synaptobrevin Homolog YKT6) is a gene that encodes a protein involved in synaptic plasticity, which is the ability of the nervous system to change and adapt over time. The protein functions as a scaffold to maintain the stability of synaptic vesicles, which are the structures that store and transmit neurotransmitters. YKT6 has been identified as a potential drug target and biomarker for various neurological disorders, including Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders.

Disease-related changes in synaptic plasticity

Synaptic plasticity is critical for the healthy function of the nervous system. It allows the brain to learn and adapt to new experiences, and it is involved in the development and maintenance of neural connections. When synaptic plasticity is impaired or abnormal, it can lead to the development of various neurological disorders, including Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders.

YKT6 plays a crucial role in maintaining synaptic plasticity

YKT6 is a key protein that helps to maintain the stability of synaptic vesicles. Synaptic vesicles are specialized structures that store and transmit neurotransmitters. They are critical for the formation and maintenance of neural connections, and they play a crucial role in synaptic plasticity. YKT6 helps to ensure that synaptic vesicles remain stable and can support the transfer of neurotransmitters across the synapse.

In Alzheimer's disease, synaptic plasticity is severely impaired, which is thought to contribute to the development and progression of the disease. Studies have shown that YKT6 levels are decreased in the brains of individuals with Alzheimer's disease, and that inhibiting YKT6 activity may be a potential therapeutic approach for the disease.

YKT6 as a drug target

YKT6 has been identified as a potential drug target for various neurological disorders, including Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders. The reason for its potential as a drug target is its involvement in synaptic plasticity and its ability to modulate the activity of other proteins involved in synaptic plasticity.

Studies have shown that YKT6 can interact with various proteins involved in synaptic plasticity, including the neurotransmitter receptors, the protein involved in synaptic plasticity (PARP), and the protein involved in the regulation of synaptic plasticity (CREB). These interactions suggest that YKT6 may have a role in modulating the activity of these proteins and their role in synaptic plasticity.

In addition, YKT6 has also been shown to interact with the protein involved in the formation of new neurons (Neuron-Specific Protein, NSP), which plays a crucial role in the development and maintenance of neural networks. This suggests that YKT6 may also be involved in the regulation of neuron formation and the organization of neural networks.

YKT6 as a biomarker

YKT6 has also been identified as a potential biomarker for various neurological disorders, including Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders. The reason for its potential as a biomarker is its involvement in synaptic plasticity and its ability to modulate the activity of other proteins involved in synaptic plasticity.

Studies have shown that YKT6 levels are decreased in the brains of individuals with Alzheimer's disease, and that the levels of YKT6 are increased in the brains of individuals with Parkinson's disease. These findings suggest that YKT6 may be a useful biomarker for the diagnosis and

Protein Name: YKT6 V-SNARE Homolog

Functions: Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity

The "YKT6 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about YKT6 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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