ZBTB49: A Drug Target / Disease Biomarker (G166793)

Target Name: ZBTB49

NCBI ID: G166793

ZBTB49

ZBTB49: A Drug Target / Disease Biomarker

ZBTB49 is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the Zinc Finger Transmembrane Protein (ZF2) family, which is known for their role in intracellular signaling. ZBTB49 has been shown to play a role in a variety of physiological processes, including cell signaling, inflammation, and neurodegeneration. As a result, ZBTB49 has potential as a drug target or biomarker.

The ZF2 family of proteins consists of at least 20 different isoforms, including ZBTB49. These proteins are characterized by a conserved N-terminal transmembrane domain and a C-terminal domain that contains a variety of different functional modules, including a zinc finger, a leucine-rich repeat, and a carboxy-terminal protein-disulfide (PDS) domain. ZBTB49 is a 21 kDa protein that is expressed in the brain, heart, and kidneys, and has been shown to play a role in a variety of physiological processes.

One of the most significant functions of ZBTB49 is its role in intracellular signaling. ZBTB49 has been shown to interact with a variety of different proteins, including the transcription factor NF-kappa-B and the protein PDGF-BB. These interactions are important for the regulation of a variety of different cellular processes, including cell signaling, inflammation, and neurodegeneration.

In addition to its role in intracellular signaling, ZBTB49 is also involved in the regulation of various cellular processes that are important for overall cellular function. For example, ZBTB49 has been shown to play a role in the regulation of cell adhesion, which is important for the maintenance of tissue structure and the development of various diseases, including cancer. ZBTB49 has also been shown to play a role in the regulation of cell migration, which is important for the development and maintenance of various tissues and organs.

In addition to its role in intracellular signaling and cellular processes, ZBTB49 has also been shown to be involved in the development and progression of neurodegenerative diseases. For example, ZBTB49 has been shown to be involved in the development of neurofibrillary tangles, which are thought to play a role in the development of Alzheimer's disease. ZBTB49 has also been shown to be involved in the regulation of the neurotransmitter serotonin, which is important for the regulation of mood and other physiological processes.

As a result of its role in a variety of physiological processes, ZBTB49 has potential as a drug target or biomarker. For example, ZBTB49 could be targeted by small molecules or antibodies that are designed to interact with ZBTB49 and disrupt its function. Such compounds could potentially be used to treat a variety of different diseases, including neurodegenerative diseases and cancer. Additionally, ZBTB49 could also be used as a biomarker for the diagnosis and monitoring of various diseases.

In conclusion, ZBTB49 is a protein that is expressed in various tissues of the body and has been shown to play a role in a variety of physiological processes. Its potential as a drug target or biomarker makes it an attractive target for further research and development. Further studies of ZBTB49 and its role in intracellular signaling and neurodegenerative diseases may lead to the development of new treatments and therapies for a variety of different conditions.

Protein Name: Zinc Finger And BTB Domain Containing 49

Functions: Transcription factor. Inhibits cell proliferation by activating either CDKN1A/p21 transcription or RB1 transcription

The "ZBTB49 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZBTB49 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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