Identification of ZAR1 as A Potential Drug Target Or Biomarker

Target Name: ZAR1

NCBI ID: G326340

ZAR1

Identification of ZAR1 as A Potential Drug Target Or Biomarker

ZAR1 (ZAR1_HUMAN), a protein that is expressed in various tissues of the human body, including the brain, heart, and gastrointestinal tract, has been identified as a potential drug target or biomarker in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

ZAR1 is a member of the ZAR family of transmembrane proteins, which are characterized by their ability to form a tight cytoskeleton and to regulate the expression of various genes in the cell. The ZAR family has been implicated in various physiological processes, including cell signaling, cell adhesion, and transcriptional regulation.

One of the unique features of ZAR1 is its ability to form a complex with other proteins that are involved in the regulation of cellular processes, including the transcription factor p53. This interaction between ZAR1 and p53 has been shown to play a role in the regulation of various cellular processes, including cell growth, apoptosis, and inflammation.

In addition to its role in cell signaling and regulation, ZAR1 has also been shown to be involved in the regulation of cellular interactions with the surrounding environment, including the extracellular matrix (ECM) and other cell-cell interactions. This involvement in ECM regulation has been implicated in the development of various diseases, including cancer, where the regulation of ECM interactions is often disrupted.

The ZAR1 protein has also been shown to be involved in the regulation of cellular processes that are important for maintaining cellular homeostasis, including the regulation of ion channels, caveolae, and other structures that are involved in the regulation of cellular membrane potential and the maintenance of cellular structure.

In conclusion, ZAR1 is a protein that has been shown to be involved in a wide range of cellular processes that are important for maintaining cellular homeostasis and regulating cellular interactions with the surrounding environment. Its potential as a drug target or biomarker makes it an attractive target for the development of new treatments for various diseases. Further research is needed to fully understand the role of ZAR1 in cellular processes and its potential as a drug target or biomarker.

Protein Name: Zygote Arrest 1

Functions: mRNA-binding protein that mediates formation of MARDO (mitochondria-associated ribonucleoprotein domain), a membraneless compartment that stores maternal mRNAs in oocytes. MARDO assembly around mitochondria is directed by an increase in mitochondrial membrane potential during oocyte growth. Promotes formation of MARDO phase-separated membraneless compartment by undergoing liquid-liquid phase separation upon binding to maternal mRNAs. Binds to the 3'-UTR of maternal mRNAs. Maternal mRNAs stored in the MARDO are translationally repressed. Essential for female fertility and oocyte-to-embryo transition by coordinating maternal mRNA storage, translation and degradation

The "ZAR1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZAR1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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