ZBTB42: A Drug Target / Disease Biomarker (G100128927)

Target Name: ZBTB42

NCBI ID: G100128927

ZBTB42

ZBTB42: A Drug Target / Disease Biomarker

ZBTB42 is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the Zonulin-protein family, which is known for their role in regulating cell-cell adhesion and signaling. ZBTB42 has been shown to play a role in a variety of physiological processes, including cell signaling, neurodegeneration, and fibrosis. As a result, ZBTB42 has potential as a drug target or biomarker in a variety of diseases.

One of the key functions of ZBTB42 is its role in cell signaling. It is a potent positive regulator of the protein F-actinin, which is involved in cell adhesion and migration. F-actinin is a protein that is expressed in various tissues, including the brain, and is known for its role in the regulation of neural circuits. By regulating F-actinin, ZBTB42 helps to control the movement of cells and the formation of tissues.

Another function of ZBTB42 is its role in neurodegeneration. neurodegeneration is a condition in which the brain and other nervous system cells die or are damaged, leading to a range of symptoms, including cognitive decline, weakness, and loss of function. ZBTB42 has been shown to be involved in the regulation of neurodegeneration, and may be a potential drug target for treatments of neurodegenerative diseases.

In addition to its role in cell signaling and neurodegeneration, ZBTB42 is also involved in the regulation of fibrosis. Fibrosis is a condition in which cells become abnormally organized and produce an excessive amount of extracellular matrix (ECM) material. This can lead to a range of diseases, including heart failure, cancer, and chronic obstructive pulmonary disease (COPD). ZBTB42 has been shown to be involved in the regulation of fibrosis, and may be a potential biomarker for the diagnosis and treatment of fibrosities.

Overall, ZBTB42 is a protein that plays a critical role in a variety of physiological processes in the body. Its functions in cell signaling, neurodegeneration, and fibrosis make it a potential drug target or biomarker in a variety of diseases. Further research is needed to fully understand the role of ZBTB42 in these processes and its potential as a therapeutic agent.

Protein Name: Zinc Finger And BTB Domain Containing 42

Functions: Transcriptional repressor. Specifically binds DNA and probably acts by recruiting chromatin remodeling multiprotein complexes

The "ZBTB42 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZBTB42 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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