ZBTB42: A Drug Target / Disease Biomarker (G100128927)
ZBTB42: A Drug Target / Disease Biomarker
ZBTB42 is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the Zonulin-protein family, which is known for their role in regulating cell-cell adhesion and signaling. ZBTB42 has been shown to play a role in a variety of physiological processes, including cell signaling, neurodegeneration, and fibrosis. As a result, ZBTB42 has potential as a drug target or biomarker in a variety of diseases.
One of the key functions of ZBTB42 is its role in cell signaling. It is a potent positive regulator of the protein F-actinin, which is involved in cell adhesion and migration. F-actinin is a protein that is expressed in various tissues, including the brain, and is known for its role in the regulation of neural circuits. By regulating F-actinin, ZBTB42 helps to control the movement of cells and the formation of tissues.
Another function of ZBTB42 is its role in neurodegeneration. neurodegeneration is a condition in which the brain and other nervous system cells die or are damaged, leading to a range of symptoms, including cognitive decline, weakness, and loss of function. ZBTB42 has been shown to be involved in the regulation of neurodegeneration, and may be a potential drug target for treatments of neurodegenerative diseases.
In addition to its role in cell signaling and neurodegeneration, ZBTB42 is also involved in the regulation of fibrosis. Fibrosis is a condition in which cells become abnormally organized and produce an excessive amount of extracellular matrix (ECM) material. This can lead to a range of diseases, including heart failure, cancer, and chronic obstructive pulmonary disease (COPD). ZBTB42 has been shown to be involved in the regulation of fibrosis, and may be a potential biomarker for the diagnosis and treatment of fibrosities.
Overall, ZBTB42 is a protein that plays a critical role in a variety of physiological processes in the body. Its functions in cell signaling, neurodegeneration, and fibrosis make it a potential drug target or biomarker in a variety of diseases. Further research is needed to fully understand the role of ZBTB42 in these processes and its potential as a therapeutic agent.
Protein Name: Zinc Finger And BTB Domain Containing 42
Functions: Transcriptional repressor. Specifically binds DNA and probably acts by recruiting chromatin remodeling multiprotein complexes
More Common Targets
ZBTB43 | ZBTB44 | ZBTB44-DT | ZBTB45 | ZBTB45P2 | ZBTB46 | ZBTB46-AS1 | ZBTB47 | ZBTB48 | ZBTB49 | ZBTB5 | ZBTB6 | ZBTB7A | ZBTB7B | ZBTB7C | ZBTB7C-AS2 | ZBTB8A | ZBTB8B | ZBTB8OS | ZBTB8OSP1 | ZBTB9 | ZC2HC1A | ZC2HC1B | ZC2HC1C | ZC3H10 | ZC3H11A | ZC3H11B | ZC3H11C | ZC3H12A | ZC3H12A-DT | ZC3H12B | ZC3H12C | ZC3H12D | ZC3H13 | ZC3H14 | ZC3H15 | ZC3H18 | ZC3H18-AS1 | ZC3H3 | ZC3H4 | ZC3H6 | ZC3H7A | ZC3H7B | ZC3H8 | ZC3HAV1 | ZC3HAV1L | ZC3HC1 | ZC4H2 | ZCCHC10 | ZCCHC12 | ZCCHC13 | ZCCHC14 | ZCCHC14-DT | ZCCHC17 | ZCCHC18 | ZCCHC2 | ZCCHC24 | ZCCHC3 | ZCCHC4 | ZCCHC7 | ZCCHC8 | ZCCHC9 | ZCRB1 | ZCWPW1 | ZCWPW2 | ZDBF2 | ZDHHC1 | ZDHHC11 | ZDHHC11B | ZDHHC12 | ZDHHC12-DT | ZDHHC13 | ZDHHC14 | ZDHHC15 | ZDHHC16 | ZDHHC17 | ZDHHC18 | ZDHHC19 | ZDHHC2 | ZDHHC20 | ZDHHC20P1 | ZDHHC20P2 | ZDHHC21 | ZDHHC22 | ZDHHC23 | ZDHHC24 | ZDHHC3 | ZDHHC4 | ZDHHC5 | ZDHHC6 | ZDHHC7 | ZDHHC8 | ZDHHC8BP | ZDHHC9 | ZEB1 | ZEB1-AS1 | ZEB2 | ZEB2-AS1 | ZER1 | ZFAND1