Target Name: CCL27
NCBI ID: G10850
Review Report on CCL27 Target / Biomarker Content of Review Report on CCL27 Target / Biomarker
CCL27
Other Name(s): C-C motif chemokine 27 | Skinkine | CC chemokine ILC | skinkine | C-C motif chemokine ligand 27 | small inducible cytokine subfamily A (Cys-Cys), member 27 | Small-inducible cytokine A27 | Small inducible cytokine subfamily A (Cys-Cys), member 27 | PESKY | Small inducible cytokine A27 | CCL27_HUMAN | chemokine (C-C motif) ligand 27 | ESKINE | small-inducible cytokine A27 | IL-11 R-alpha-locus chemokine | ILC | CTAK | ESkine | Cutaneous T-cell attracting chemokine | SCYA27 | CTACK | cutaneous T-cell attracting chemokine | IL-11 Ralpha-locus chemokine | Cutaneous T-cell-attracting chemokine | ALP

CCL27: Regulation of T Cell and Immune Cell Function

CCL27, also known as C-C motif chemokine 27, is a protein that is expressed in various tissues throughout the body. It is a member of the chemokine family, which are a group of small proteins that are involved in the regulation of cellular immune responses. CCL27 is characterized by the presence of a C-C motif, which is a specific type of protein domain that is found in many proteins and is involved in various cellular processes.

The CCL27 protein is involved in the regulation of T cell responses, which are a crucial part of the immune system. T cells are a type of immune cell that play a critical role in protecting the body against infection and disease. They are able to recognize and respond to specific antigens, which are molecules that are produced by the body's cells as a response to the presence of an invading pathogen.

CCL27 is involved in the regulation of T cell responses by helping to coordinate the signaling processes that occur between T cells and the immune system's other components. It does this by participating in a signaling pathway that is known as the T cell signaling cascade. This pathway is responsible for ensuring that T cells are able to recognize and respond to specific antigens, and for regulating the production and activation of T cells.

One of the ways that CCL27 is involved in this process is by regulating the activity of a protein called PD-1. PD-1 is a protein that is expressed in many different types of cells, including T cells. It is involved in the regulation of T cell responses by helping to control the activity of T cells that are able to recognize and respond to specific antigens. CCL27 has been shown to play a role in regulating the activity of PD-1, which may help to ensure that T cells are able to recognize and respond to specific antigens.

Another way that CCL27 is involved in the regulation of T cell responses is by regulating the activity of a protein called NF-kappa-B. NF-kappa-B is a protein that is involved in the regulation of many different cellular processes, including those that are related to inflammation and infection. CCL27 has been shown to play a role in regulating the activity of NF-kappa-B, which may help to ensure that T cells are able to respond to invading pathogens in an effective manner.

CCL27 is also involved in the regulation of inflammation and immune responses in other ways. For example, it has been shown to play a role in the regulation of the production of pro-inflammatory cytokines, which are molecules that are released by immune cells in response to the presence of an invading pathogen. CCL27 may also be involved in the regulation of the activation and function of immune cells, such as T cells and macrophages.

In addition to its role in regulating T cell responses, CCL27 is also involved in the regulation of inflammation and immune responses in other ways. For example, it has been shown to play a role in the regulation of the production of antibodies, which are proteins that are produced by the immune system in response to the presence of an invading pathogen. CCL27 may also be involved in the regulation of the activation and function of immune cells, such as T cells and macrophages.

Overall, CCL27 is a protein that is involved in a wide range of cellular processes that are important for the regulation of T cell responses and the immune system as a whole. Its role in these processes makes it an attractive target for research into the development of new drugs or therapies for a variety of diseases.

Protein Name: C-C Motif Chemokine Ligand 27

Functions: Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. Binds to CCR10

The "CCL27 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CCL27 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

CCL28 | CCL3 | CCL3-AS1 | CCL3L1 | CCL3L3 | CCL3P1 | CCL4 | CCL4L1 | CCL4L2 | CCL5 | CCL7 | CCL8 | CCM2 | CCM2L | CCN1 | CCN2 | CCN3 | CCN4 | CCN5 | CCN6 | CCNA1 | CCNA2 | CCNB1 | CCNB1IP1 | CCNB2 | CCNB2P1 | CCNB3 | CCNC | CCND1 | CCND2 | CCND2-AS1 | CCND3 | CCNDBP1 | CCNE1 | CCNE2 | CCNF | CCNG1 | CCNG2 | CCNH | CCNI | CCNI2 | CCNJ | CCNJL | CCNK | CCNL1 | CCNL2 | CCNO | CCNP | CCNQ | CCNQP1 | CCNT1 | CCNT2 | CCNT2-AS1 | CCNT2P1 | CCNY | CCNYL1 | CCNYL2 | CCP110 | CCPG1 | CCR1 | CCR10 | CCR12P | CCR2 | CCR3 | CCR4 | CCR4-NOT transcription complex | CCR5 | CCR5AS | CCR6 | CCR7 | CCR8 | CCR9 | CCRL2 | CCS | CCSAP | CCSER1 | CCSER2 | CCT2 | CCT3 | CCT4 | CCT5 | CCT6A | CCT6B | CCT6P1 | CCT6P3 | CCT7 | CCT8 | CCT8L1P | CCT8L2 | CCT8P1 | CCZ1 | CCZ1B | CCZ1P-OR7E38P | CD101 | CD101-AS1 | CD109 | CD14 | CD151 | CD160 | CD163