CCR10: A Protein Involved in Immune and Neurotransmission (G2826)
CCR10: A Protein Involved in Immune and Neurotransmission
CCR10, also known as CC chemokine receptor type 10, is a protein that is expressed in a variety of cell types, including immune cells, neurons, and tissues. It is a member of the chemokine receptor family, which is a group of transmembrane proteins that play a critical role in the regulation of cellular responses to various stimuli, including viruses and cancer cells.
CCR10 is a G protein-coupled receptor (GPCR), which means that it uses a protein called transmembrane spanning domain (TM) to communicate with intracellular signaling pathways. When CCR10 is activated, it causes a range of downstream signaling cascades that ultimately result in the production of various cytokines and chemokines, as well as changes in cellular behavior and survival.
One of the key functions of CCR10 is its role in the regulation of immune cell responses to infection and inflammation. CCR10 is known to play a critical role in the development of an effective immune response to viruses, including HIV, that is characterized by the production of interferon and other cytokines.
In addition to its role in immune responses, CCR10 is also involved in the regulation of neurotransmitter signaling and neurodevelopment. For example, studies have shown that CCR10 is involved in the regulation of the release of neurotransmitters, such as dopamine and serotonin, and that it plays a role in the development of neurodegenerative diseases.
CCR10 is also a potential drug target for several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, studies have shown that CCR10 is involved in the regulation of the growth and survival of cancer cells and that inhibiting its activity may be an effective way to treat cancer.
In addition, CCR10 has also been shown to be involved in the regulation of pain perception and neuroinflammation, which may make it an attractive target for the treatment of neuropathic pain.
In conclusion, CCR10 is a protein that plays a critical role in the regulation of various cellular processes, including immune responses, neurotransmission and development. It is a potential drug target for several diseases and may be a valuable tool for the development of new treatments. Further research is needed to fully understand the role of CCR10 in cellular processes and its potential as a drug target.
Protein Name: C-C Motif Chemokine Receptor 10
Functions: Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis in a pre-B cell line
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CCR12P | CCR2 | CCR3 | CCR4 | CCR4-NOT transcription complex | CCR5 | CCR5AS | CCR6 | CCR7 | CCR8 | CCR9 | CCRL2 | CCS | CCSAP | CCSER1 | CCSER2 | CCT2 | CCT3 | CCT4 | CCT5 | CCT6A | CCT6B | CCT6P1 | CCT6P3 | CCT7 | CCT8 | CCT8L1P | CCT8L2 | CCT8P1 | CCZ1 | CCZ1B | CCZ1P-OR7E38P | CD101 | CD101-AS1 | CD109 | CD14 | CD151 | CD160 | CD163 | CD163L1 | CD164 | CD164L2 | CD177 | CD177P1 | CD180 | CD19 | CD1A | CD1B | CD1C | CD1D | CD1E | CD2 | CD200 | CD200R1 | CD200R1L | CD207 | CD209 | CD22 | CD226 | CD24 | CD244 | CD247 | CD248 | CD24P2 | CD27 | CD27-AS1 | CD274 | CD276 | CD28 | CD2AP | CD2BP2 | CD3 Complex (T Cell Receptor Complex) | CD300A | CD300C | CD300E | CD300LB | CD300LD | CD300LD-AS1 | CD300LF | CD300LG | CD302 | CD320 | CD33 | CD34 | CD36 | CD37 | CD38 | CD3D | CD3E | CD3G | CD4 | CD40 | CD40LG | CD44 | CD44-DT | CD46 | CD47 | CD48 | CD5 | CD52
