Target Name: MGLL
NCBI ID: G11343
Review Report on MGLL Target / Biomarker Content of Review Report on MGLL Target / Biomarker
MGLL
Other Name(s): HUK5 | MGLL variant 1 | Monoacylglycerol lipase | lysophospholipase homolog | MGLL variant 2 | monoacylglycerol lipase | MGLL_HUMAN | Monoglyceride lipase (isoform 2) | MGL | Monoglyceride lipase (isoform 1) | monoglyceride lipase | Monoglyceride lipase (isoform 3) | HU-K5 | Monoglyceride lipase | MGLL variant 3 | Lysophospholipase-like | Lysophospholipase homolog | MAGL

MGLL's Role in Diseases

MGLL (HUK5) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a key regulator of cell growth and differentiation, and has been implicated in a number of diseases, including cancer.

One of the key functions of MGLL is its role in cell signaling. It is a transcription factor that regulates the expression of genes, and it has been shown to play a role in a variety of cellular processes, including cell division, migration, and survival.

MGLL has also been shown to play a key role in the development and progression of cancer. Studies have shown that MGLL levels are elevated in a variety of cancer types, and that inhibiting its activity can lead to the growth and progression of cancer.

In addition to its role in cancer, MGLL is also implicated in a number of other diseases. For example, it has been shown to be involved in the development of cardiovascular disease, and to contribute to the development of neurodegenerative diseases.

Despite these promising findings, much more research is needed to fully understand the role of MGLL in diseases. Researchers are currently working to develop new treatments for cancer and other diseases based on MGLL, and to determine the best way to use it as a drug target.

In conclusion, MGLL is a protein that is expressed in various tissues throughout the body, and it has been implicated in a number of diseases, including cancer. Further research is needed to fully understand its role in these diseases and to develop new treatments based on it.

Protein Name: Monoglyceride Lipase

Functions: Converts monoacylglycerides to free fatty acids and glycerol (PubMed:19029917, PubMed:20079333, PubMed:21049984, PubMed:22969151, PubMed:24368842). Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (PubMed:19029917, PubMed:20079333, PubMed:21049984, PubMed:22969151, PubMed:24368842). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth (PubMed:20079333)

The "MGLL Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MGLL comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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MGME1 | MGMT | MGP | MGRN1 | MGST1 | MGST2 | MGST3 | MHRT | MIA | MIA-RAB4B | MIA2 | MIA3 | MIAT | MIATNB | MIB1 | MIB2 | MICA | MICA-AS1 | MICAL1 | MICAL2 | MICAL3 | MICALCL | MICALL1 | MICALL2 | MICB | MICB-DT | MICC | MICD | MICOS10 | MICOS10-NBL1 | MICOS10P1 | MICOS13 | Microfilament-associated triple complex | MicroRNA 1273d | MicroRNA 1273f | MicroRNA 1273g | MicroRNA 3607 | MicroRNA 3653 | MicroRNA 3656 | MicroRNA 4417 | MicroRNA 4419a | MicroRNA 4459 | MicroRNA 4461 | MicroRNA 4532 | MicroRNA 4792 | MicroRNA 5095 | MicroRNA 5096 | MicroRNA 6087 | MicroRNA 6723 | MicroRNA 7641-1 | MicroRNA 7641-2 | Microtubule-Associated Protein | MICU1 | MICU2 | MICU3 | MID1 | MID1IP1 | MID1IP1-AS1 | MID2 | MIDEAS | MIDEAS-AS1 | MIDN | MIEF1 | MIEF2 | MIEN1 | MIER1 | MIER2 | MIER3 | MIF | MIF-AS1 | MIF4GD | MIGA1 | MIGA2 | MIIP | MILIP | MILR1 | MIMT1 | MINAR1 | MINAR2 | MINCR | MINDY1 | MINDY2 | MINDY2-DT | MINDY3 | MINDY4 | Minichromosome maintenance (MCM) 2-7 helicase complex | MINK1 | MINPP1 | MIOS | MIOX | MIP | MIPEP | MIPEPP3 | MIPOL1 | MIR1-1 | MIR1-1HG | MIR1-2 | MIR100 | MIR100HG | MIR101-1