CLIP3: A Protein Regulator of The Immune Response (G25999)

Target Name: CLIP3

NCBI ID: G25999

CLIP3

CLIP3: A Protein Regulator of The Immune Response

CLIP3 (CLIPR59) is a protein that is expressed in the immune cells of the body. It is a key regulator of the cytokine network, which is a complex system of signaling molecules that play a crucial role in the immune response. CLIP3 is also a potential drug target and biomarker for several diseases, including cancer, autoimmune disorders, and neurodegenerative diseases.

CLIP3 is a transmembrane protein that is expressed in the cytoplasm of various cell types. It is composed of four structural domains: an N-terminus, a T-terminus, a middle domain, and an C-terminus. The N-terminus of CLIP3 contains a putative extracellular domain (ECD) that is involved in its stability and functions as a receptor. The T-terminus of CLIP3 contains a variable region (V1) that is involved in the formation of the cytokine receptor complex. The middle domain of CLIP3 contains a transmembrane region (TM) that is involved in the regulation of intracellular signaling pathways. The C-terminus of CLIP3 contains a cytoplasmic domain (CPD) that is involved in the regulation of cellular processes such as cytoskeletal organization and cell adhesion.

CLIP3 is a key regulator of the cytokine network, which is a complex system of signaling molecules that play a crucial role in the immune response. Cytokines are small signaling proteins that are produced by the immune cells in response to the presence of foreign substances in the body. These cytokines can stimulate a variety of cellular processes, including cell adhesion, migration, and activation of signaling pathways that are involved in the immune response.

CLIP3 is involved in the regulation of several key signaling pathways that are involved in the immune response. One of the most significant roles of CLIP3 is in the regulation of the T-cell receptor (TCR) signaling pathway. TCR is a key signaling pathway that is involved in the regulation of T-cell proliferation, differentiation, and activation. CLIP3 is involved in the regulation of TCR signaling by controlling the activity of the protein kinase PD-L1. PD-L1 is a negative regulator of PD-L1, which is involved in the regulation of TCR signaling.

In addition to its role in TCR signaling, CLIP3 is also involved in the regulation of several other signaling pathways that are involved in the immune response. For example, CLIP3 is involved in the regulation of the chemokine receptor (CXCR) signaling pathway, which is involved in the regulation of cell adhesion and migration. CLIP3 is also involved in the regulation of the NF-kappa-B signaling pathway, which is involved in the regulation of inflammation and inflammation-related processes.

CLIP3 is a potential drug target and biomarker for several diseases, including cancer, autoimmune disorders, and neurodegenerative diseases. For example, CLIP3 has been shown to be overexpressed in several types of cancer, including breast cancer, lung cancer, and colon cancer. This suggests that CLIP3 may be a useful target for cancer therapies that target the immune cells that are involved in these cancers. In addition, CLIP3 has also been shown to be involved in the regulation of the immune response, which suggests that it may be a useful target for diseases that are characterized by inflammation and inflammation-related processes.

CLIP3 is also a potential biomarker for several diseases, including cancer, autoimmune disorders, and neurodegenerative diseases. For example, studies have shown that CLIP3 levels are elevated in the blood of patients with breast cancer, which suggests that CLIP3 may be a useful biomarker for this disease. In addition, CLIP3 has

Protein Name: CAP-Gly Domain Containing Linker Protein 3

Functions: Functions as a cytoplasmic linker protein. Involved in TGN-endosome dynamics. May modulate the cellular compartmentalization of AKT kinase family and promote its cell membrane localization, thereby playing a role in glucose transport in adipocytes

The "CLIP3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CLIP3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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