Unlocking The Potential of Peroxidasin-like Protein PXDNL (G137902)

Target Name: PXDNL

NCBI ID: G137902

PXDNL

Unlocking The Potential of Peroxidasin-like Protein PXDNL

Peroxidasin-like protein (PXDNL) is a protein that is expressed in various tissues throughout the body. It is characterized by its unique structure, which is similar to that of peroxidasins, a class of enzymes that are involved in cellular signaling. While peroxidasins are Known for their ability to catalyze the oxidation of thiylidium ions to form peroxides, PXDNL is different in that it does not have a catalytic activity. Instead, it is involved in the regulation of cellular signaling pathways, specifically those that are related to cell adhesion, migration, and survival.

One of the unique features of PXDNL is its ability to interact with various signaling molecules, including F-actinin, a protein that is involved in cell adhesion and migration. F-actinin is a cytoplasmic protein that is known for its ability to interact with PXDNL and to regulate the activity of the protein tyrosine kinase (TK).

PXDNL is also involved in the regulation of the cytoskeleton, which is the structure that gives cells their shape and helps them to move and function. It is known to interact with the protein tubulin (MAPT), which is involved in the regulation of microtubule dynamics and stability.

In addition to its role in regulating cellular signaling pathways, PXDNL is also involved in the regulation of cell survival. It has been shown to play a role in the regulation of cell apoptosis, which is the process by which cells undergo programmed cell death. This is done through its ability to interact with the protein Bcl-2 (Bcl-2-associated protein 2), which is involved in the regulation of cell apoptosis.

Despite its involvement in a number of important cellular processes, the function and significance of PXDNL are not yet fully understood. While it is known to play a role in the regulation of cell adhesion, migration, and survival, it is not clear what its specific function is or how it contributes to these processes. Further research is needed to fully understand the role of PXDNL in cellular biology.

In addition to its potential as a drug target, PXDNL may also be a valuable biomarker for the diagnosis and prognosis of certain diseases. For example, its involvement in the regulation of cell apoptosis may be a potential therapeutic target for certain types of cancer. Additionally , its ability to interact with F-actinin and MAPT may be involved in the regulation of cell adhesion and migration, which could be useful for the diagnosis and treatment of certain diseases such as cardiovascular disease and neurological disorders.

Overall, PXDNL is a protein that is involved in a number of important cellular processes. While its specific function is not yet fully understood, its potential as a drug target and biomarker make it an attractive target for further research. Further studies may reveal its full potential in the regulation of cellular biology and its role in the diagnosis and treatment of disease.

Protein Name: Peroxidasin Like

Functions: Probable oxidoreductase (Probable). Lacks peroxidase activity (PubMed:24253521). Inhibits the peroxidase activity of PXDN through its interaction (PubMed:24253521)

The "PXDNL Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PXDNL comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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