RAB23: A Protein Involved in Cell Signaling and Cell Migration

Target Name: RAB23

NCBI ID: G51715

RAB23

RAB23: A Protein Involved in Cell Signaling and Cell Migration

RAB23 is a protein that is expressed in many different tissues throughout the body. It is a member of the Rab family of proteins, which are known for their role in cell signaling and transduction. RAB23 is highly conserved across various species, and it has been implicated in a number of different biological processes.

One of the most significant roles of RAB23 is in the regulation of cell signaling pathways. It is a key regulator of the RhoA GTPase, which is a protein that is involved in cell signaling and cell division. RAB23 functions as a negative regulator of RhoA, which means that it keeps the level of RhoA low, which in turn inhibits the activity of the RhoA GTPase.

Another function of RAB23 is in the regulation of cell adhesion. It is a critical regulator of the cadherin protein, which is involved in cell-cell adhesion. RAB23 functions as a positive regulator of cadherin, which means that it increases the level of cadherin, which in turn promotes cell-cell adhesion.

RAB23 is also involved in the regulation of cell migration. It is a critical regulator of the protein vimentin, which is involved in cell migration. RAB23 functions as a negative regulator of vimentin, which means that it keeps the level of vimentin low, which in turn inhibits cell migration.

In addition to its role in cell signaling and cell adhesion, RAB23 is also involved in the regulation of cell cycle progression. It is a critical regulator of the protein p21, which is involved in the regulation of cell cycle progression. RAB23 functions as a positive regulator of p21, which means that it increases the level of p21, which in turn promotes the regulation of cell cycle progression.

RAB23 is highly conserved across various species, and it has been implicated in a number of different biological processes. It is a potential drug target, and researchers are currently studying its potential uses in the treatment of various diseases. For example, RAB23 has been shown to be involved in the regulation of cancer cell growth, and it is thought to be a useful target for cancer therapies. Additionally, RAB23 has also been shown to be involved in the regulation of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

In conclusion, RAB23 is a protein that is involved in a number of different biological processes. It is a potential drug target, and researchers are currently studying its potential uses in the treatment of various diseases. Further research is needed to fully understand the role of RAB23 in cell signaling and cell biology, and to determine its potential as a drug target.

Protein Name: RAB23, Member RAS Oncogene Family

Functions: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Together with SUFU, prevents nuclear import of GLI1, and thereby inhibits GLI1 transcription factor activity. Regulates GLI1 in differentiating chondrocytes. Likewise, regulates GLI3 proteolytic processing and modulates GLI2 and GLI3 transcription factor activity. Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that then merge with lysosomes

The "RAB23 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RAB23 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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