Target Name: R3HDML
NCBI ID: G140902
Review Report on R3HDML Target / Biomarker Content of Review Report on R3HDML Target / Biomarker
R3HDML
Other Name(s): R3H domain containing like | dJ881L22.3 | CRSPL_HUMAN | cysteine-rich secretory protein R3HDML | Peptidase inhibitor R3HDML | R3H domain (binds single-stranded nucleic acids) containing-like | Cysteine-rich secretory protein R3HDML

R3HDML: A Protein Regulator of Hematopoietic Stem Cells and Neurodevelopmental Disorders

R3HDML, also known as R3-HDML, is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a key regulator of the hematopoietic stem cell (HSC) and has been implicated in the development and maintenance of various diseases, including cancer.

The R3HDML gene was first identified in 2008 and has since been shown to encode a protein that is expressed in the bone marrow, spleen, heart, and kidneys. The protein is composed of four domains: a N-terminal transmembrane domain, a single- chain variable region (SCVR), a coiled-coil domain, and a C-terminal T-cell receptor alpha-like domain (TCR-伪-like).

Functions and Interactions

R3HDML is a critical regulator of the hematopoietic stem cell (HSC) proliferation and differentiation. It has been shown to play a role in the development and maintenance of various diseases, including cancer. R3HDML has been shown to promote the self-renewal and proliferation of HSCs, and it has been implicated in the development of leukemia, bone marrow disorders, and other diseases.

In addition to its role in HSCs, R3HDML has also been shown to play a critical role in the development and maintenance of the nervous system. It has been shown to be involved in the development and maintenance of neuronal stem cells, and it has been implicated in the development of various neurological disorders, including Alzheimer's disease and Parkinson's disease.

R3HDML has also been shown to play a critical role in the regulation of inflammation. It has been shown to be involved in the regulation of T cell responses, and it has been implicated in the development and maintenance of various inflammatory diseases, including rheumatoid arthritis and multiple sclerosis.

Drug Interpretation and Targeting

R3HDML is a drug target that has potential for the development of new treatments for various diseases. Because it

Protein Name: R3H Domain Containing Like

Functions: Putative serine protease inhibitor

The "R3HDML Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about R3HDML comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

R3HDML-AS1 | RAB GTPase | RAB10 | RAB11A | RAB11AP2 | RAB11B | RAB11B-AS1 | RAB11FIP1 | RAB11FIP2 | RAB11FIP3 | RAB11FIP4 | RAB11FIP5 | RAB12 | RAB13 | RAB14 | RAB15 | RAB17 | RAB18 | RAB19 | RAB1A | RAB1B | RAB20 | RAB21 | RAB22A | RAB23 | RAB24 | RAB25 | RAB26 | RAB27A | RAB27B | RAB28 | RAB29 | RAB2A | RAB2B | RAB3 GTPase activating protein | RAB30 | RAB30-DT | RAB31 | RAB32 | RAB33A | RAB33B | RAB34 | RAB35 | RAB36 | RAB37 | RAB38 | RAB39A | RAB39B | RAB3A | RAB3B | RAB3C | RAB3D | RAB3GAP1 | RAB3GAP2 | RAB3IL1 | RAB3IP | RAB40A | RAB40AL | RAB40B | RAB40C | RAB41 | RAB42 | RAB42P1 | RAB43 | RAB43P1 | RAB44 | RAB4A | RAB4B | RAB4B-EGLN2 | RAB5A | RAB5B | RAB5C | RAB5IF | RAB6A | RAB6B | RAB6C | RAB6C-AS1 | RAB6D | RAB7A | RAB7B | RAB8A | RAB8B | RAB9A | RAB9B | RAB9BP1 | RABAC1 | RABEP1 | RABEP2 | RABEPK | RABGAP1 | RABGAP1L | RABGAP1L-DT | RABGEF1 | RABGEF1P1 | RABGGTA | RABGGTB | RABIF | RABL2A | RABL2B | RABL3