RAB3IL1: A Potential Drug Target and Biomarker for Rab-3A (ISO Form 1)

Target Name: RAB3IL1

NCBI ID: G5866

RAB3IL1

RAB3IL1: A Potential Drug Target and Biomarker for Rab-3A (ISO Form 1)

Rab-3A, a small G protein-coupled receptor (GPCR), is involved in various physiological processes, including cell signaling, neurotransmission, and sensory perception. The protein is expressed in many different tissues and cells in the body, making it an attractive target for drug development. GPCRs are a family of transmembrane proteins that play a crucial role in cellular signaling, and the loss of GPCRs can lead to various diseases, including neurodegenerative disorders, cancer, and cardiovascular diseases.

RAB3IL1, a GPCR-associated protein, has been identified as a potential drug target and biomarker for Rab-3A. In this article, we will discuss the biology of Rab-3A, the function of RAB3IL1, and its potential as a drug target.

Biography of Rab-3A

Rab-3A is a 21-kDa protein that is expressed in the brain and other nervous tissue. It is a GPCR that is involved in the regulation of neural circuits, including the transmission of signals from the dendrites to the cell body and the generation of action potentials. Rab-3A is composed of an extracellular loop, a transmembrane domain, and an intracellular domain. The extracellular loop is involved in the formation of the protein's N-terminus, and the transmembrane domain is responsible for the interaction between Rab-3A and its ligands. The intracellular domain is involved in the regulation of the protein's stability and function.

Function of RAB3IL1

RAB3IL1 is a protein that is highly conserved across various species, including humans. It is a GPCR-associated protein that is involved in the regulation of various cellular processes, including neurotransmission, cell signaling, and cell survival. One of the functions of RAB3IL1 is to regulate the activity of Rab-3A, a GPCR that is involved in the regulation of neural circuits.

RAB3IL1 functions as a negative regulator of Rab-3A. It binds to the N-terminus of Rab-3A and prevents the protein from being phosphorylated, which is necessary for its function. This interaction between RAB3IL1 and Rab-3A is critical for the regulation of neural circuits and the maintenance of brain health.

Potential Drug Target

RAB3IL1 is a potential drug target for the treatment of various psychiatric and neurological disorders, including Alzheimer's disease, Parkinson's disease, and schizophrenia. These disorders are characterized by the progressive loss of brain cells and the development of neurodegeneration. By targeting RAB3IL1, researchers may be able to reduce the number of neurodegenerate cells and improve brain function in individuals with these disorders.

RAB3IL1 is also a potential biomarker for the diagnosis and progression of these disorders. The loss of RAB3IL1 has been observed in the brains of individuals with Alzheimer's disease and other neurological disorders. This suggests that RAB3IL1 may be a useful biomarker for the diagnosis and progression of these disorders.

Conclusion

RAB3IL1 is a protein that is involved in the regulation of various cellular processes, including neurotransmission and cell signaling. It is a potential drug target and biomarker for the treatment of psychiatric and neurological disorders. By targeting RAB3IL1, researchers may be able to improve brain function and reduce the number of neurodegenerate cells in individuals with these disorders. Further studies are needed to determine the full potential of RAB3IL1 as a drug target and biomarker.

Protein Name: RAB3A Interacting Protein Like 1

Functions: Guanine nucleotide exchange factor (GEF) which may activate RAB3A, a GTPase that regulates synaptic vesicle exocytosis. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May also activate RAB8A and RAB8B

The "RAB3IL1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RAB3IL1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
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•   the target screening and validation;
•   expression level;
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•   related combination drugs;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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