CXCL11: A Protein Involved in Multiple Cellular Processes and Potential Drug Target

Target Name: CXCL11

NCBI ID: G6373

CXCL11

CXCL11: A Protein Involved in Multiple Cellular Processes and Potential Drug Target

CXCL11, also known as IP9, is a protein that is expressed in various tissues throughout the body, including the brain, lungs, heart, kidneys, and intestines. It is a member of the Intercellular Signaling (ICIS) family, which is known for its role in various cellular processes, including inflammation, fibrosis, and cancer.

One of the most significant aspects of CXCL11 is its role in cancer. CXCL11 has been shown to promote the growth and survival of various types of cancer cells, including breast, lung, and ovarian cancer. This is achieved through several mechanisms, including the regulation of cell adhesion, the production of pro-inflammatory cytokines, and the inhibition of apoptosis.

Another important function of CXCL11 is its role in inflammation. CXCL11 has been shown to play a key role in the regulation of inflammatory responses, both in the context of infection and in the context of autoimmune diseases. In addition, CXCL11 has been shown to promote the recruitment of immune cells to sites of infection or injury, which is important for the immune response to disease.

CXCL11 is also of interest as a potential drug target. Because CXCL11 is involved in multiple cellular processes that are important for both normal and disease, it is a promising target for the development of new pharmaceuticals. For example, CXCL11 has been shown to be involved in the regulation of cell adhesion, which is important for the development of cancer. Therefore, drugs that can inhibit CXCL11 activity may be effective in treating a variety of diseases, including cancer.

In addition, CXCL11 has also been shown to be involved in the regulation of inflammation, which is important for the development of autoimmune diseases. Therefore, drugs that can inhibit CXCL11 activity may be effective in treating autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis.

CXCL11 is also of interest as a potential biomarker for cancer. Because CXCL11 is expressed in a variety of tissues throughout the body, it may be a useful indicator of the presence of cancer. Therefore, CXCL11 levels may be a useful diagnostic tool for cancer detection and monitoring.

In conclusion, CXCL11 is a protein that is expressed in various tissues throughout the body that is involved in multiple cellular processes that are important for both normal and disease. Its role in cancer and inflammation makes it an attractive target for the development of new pharmaceuticals and a potential biomarker for cancer detection. Further research is needed to fully understand the role of CXCL11 in cellular processes and its potential as a drug target and biomarker.

Protein Name: C-X-C Motif Chemokine Ligand 11

Functions: Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses

The "CXCL11 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CXCL11 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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