Target Name: CXXC4
NCBI ID: G80319
Review Report on CXXC4 Target / Biomarker Content of Review Report on CXXC4 Target / Biomarker
CXXC4
Other Name(s): OTTHUMP00000161763 | Dvl-binding protein IDAX (inhibition of the Dvl and Axin complex) | CXXC-type zinc finger protein 4 | CXXC finger protein 4 | MGC149872 | Inhibition of the Dvl and axin complex protein | IDAX | CXXC4_HUMAN | CXXC finger 4 | inhibition of the Dvl and axin complex protein

CXXC4: A Potential Drug Target and Biomarker for Cancer

CXXC4, also known as OTTHUMP00000161763, is a protein that is expressed in various tissues throughout the body. It is a key regulator of cell growth and has been implicated in a number of diseases, including cancer.

One of the most promising aspects of CXXC4 is its potential as a drug target. CXXC4 has been shown to play a role in a variety of cellular processes, including cell division, angiogenesis, and immune response. It has also been shown to interact with a number of different proteins, including TGF-β1, which is a key regulator of cell growth and differentiation.

In addition to its potential as a drug target, CXXC4 has also been shown to be a valuable biomarker for a number of diseases. For example, CXXC4 has been shown to be upregulated in a variety of cancer types, including breast, ovarian, and prostate cancer. This suggests that it may be a useful biomarker for these cancers, and that it may help doctors to diagnose and monitor these diseases more effectively.

CXXC4 is also of interest to researchers because of its complex structure. The CXXC4 protein is composed of 254 amino acids and has a calculated molecular mass of 31.9 kDa. It has a number of conserved features, including a 21 amino acid alpha-helic acid loop and a 10 amino acid beta-sheet. These features suggest that CXXC4 may be a protein that is involved in a number of important cellular processes.

In addition to its potential as a drug target and as a biomarker, CXXC4 is also of interest to researchers because of its potential role in the development of cancer. Studies have shown that CXXC4 is highly expressed in a variety of cancer types, including breast, ovarian, and prostate cancer. This suggests that it may be involved in the development and progression of these diseases.

Overall, CXXC4 is a protein that has the potential to be a drug target and a biomarker for a variety of diseases. Further research is needed to fully understand its role in these processes and to develop effective treatments for these diseases.

Protein Name: CXXC Finger Protein 4

Functions: Acts as a negative regulator of the Wnt signaling pathway via its interaction with DVL1 (By similarity). Binds preferentially to DNA containing cytidine-phosphate-guanosine (CpG) dinucleotides over CpH (H=A, T, and C), hemimethylated-CpG and hemimethylated-hydroxymethyl-CpG (PubMed:29276034)

The "CXXC4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CXXC4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

CXXC4-AS1 | CXXC5 | CYB561 | CYB561A3 | CYB561D1 | CYB561D2 | CYB5A | CYB5B | CYB5D1 | CYB5D2 | CYB5R1 | CYB5R2 | CYB5R3 | CYB5R4 | CYB5RL | CYBA | CYBB | CYBC1 | CYBRD1 | CYC1 | Cyclin | Cyclin A | Cyclin B | Cyclin D | Cyclin D2-CDK4 complex | Cyclin-dependent kinase | Cyclin-dependent kinase inhibitor | Cyclooxygenase (COX) | Cyclophilins | CYCS | CYCSP25 | CYCSP34 | CYCSP38 | CYCSP51 | CYCSP52 | CYCSP53 | CYCSP55 | CYFIP1 | CYFIP2 | CYGB | CYLC1 | CYLC2 | CYLD | CYLD-AS1 | CYMP | CYP11A1 | CYP11B1 | CYP11B2 | CYP17A1 | CYP19A1 | CYP1A1 | CYP1A2 | CYP1B1 | CYP1B1-AS1 | CYP20A1 | CYP21A1P | CYP21A2 | CYP24A1 | CYP26A1 | CYP26B1 | CYP26C1 | CYP27A1 | CYP27B1 | CYP27C1 | CYP2A13 | CYP2A6 | CYP2A7 | CYP2A7P1 | CYP2B6 | CYP2B7P | CYP2C18 | CYP2C19 | CYP2C61P | CYP2C8 | CYP2C9 | CYP2D6 | CYP2D7 | CYP2D8P | CYP2E1 | CYP2F1 | CYP2F2P | CYP2G1P | CYP2J2 | CYP2R1 | CYP2S1 | CYP2T1P | CYP2U1 | CYP2U1-AS1 | CYP2W1 | CYP39A1 | CYP3A4 | CYP3A43 | CYP3A5 | CYP3A51P | CYP3A7 | CYP3A7-CYP3A51P | CYP3AP2 | CYP46A1 | CYP4A11 | CYP4A22