CXCL5: Neutrophil Activating Protein with Multiple Functions (G6374)

Target Name: CXCL5

NCBI ID: G6374

CXCL5

CXCL5: Neutrophil Activating Protein with Multiple Functions

CXCL5 (Epithelial-Derived Neutrophil-Activating Protein 78) is a protein that is expressed in various tissues, including the epithelial tissue. It is a member of the CXCR4 family, which is known for its role in cell-cell adhesion and signaling. CXCL5 has been shown to have various functions, including the regulation of cell proliferation, differentiation, and survival.

One of the key functions of CXCL5 is its ability to activate neutrophils, which are a type of white blood cell that play a crucial role in the immune system. Neutrophils are derived from the epithelial tissue and are responsible for protecting the body against infection and inflammation . When CXCL5 is activated, it causes neutrophils to migrate to the site of infection or inflammation, where they can help to clear the pathogen or reduce inflammation.

CXCL5 has also been shown to play a role in the regulation of cell proliferation and differentiation. Neutrophils are a type of stem cell that have the ability to differentiate into different cell types. CXCL5 has also been shown to regulate the proliferation of neutrophils, allowing them to divide and differentiate into functional neutrophils that are capable of responding to an infection or inflammation.

In addition to its role in cell signaling, CXCL5 has also been shown to have important structural functions. It is a member of the CXCR4 family, which is known for its role in cell-cell adhesion and signaling. This allows CXCL5 to interact with other proteins that are part of the same family, including the protein PDGF-BB. This interaction between CXCL5 and PDGF-BB allows for the regulation of cell signaling and cell-cell adhesion.

CXCL5 has also been shown to have important regulatory functions. It is a negative regulator of the transcription factor AP-1, which is responsible for the regulation of gene expression. This means that when CXCL5 is activated, it can inhibit the activity of AP- 1, which allows for the regulation of gene expression.

CXCL5 has also been shown to have important signaling functions. It is a member of the FGFR signaling pathway, which is responsible for the regulation of cell signaling. This allows CXCL5 to interact with other proteins that are part of the FGFR signaling pathway, including the protein FGFR1. This interaction between CXCL5 and FGFR1 allows for the regulation of cell signaling and the development of cancer.

In conclusion, CXCL5 is a protein that has various functions in various tissues, including the regulation of cell proliferation, differentiation, and signaling. Its role in cell signaling and its interaction with other proteins make it an attractive drug target and a potential biomarker for various diseases. Further research is needed to fully understand the functions of CXCL5 and its potential as a drug.

Protein Name: C-X-C Motif Chemokine Ligand 5

Functions: Involved in neutrophil activation. In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes

The "CXCL5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CXCL5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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