CXXC5: A Potential Drug Target for Cancer and Other Diseases (G51523)

Target Name: CXXC5

NCBI ID: G51523

CXXC5

CXXC5: A Potential Drug Target for Cancer and Other Diseases

CXXC5, or Complement Component 5, is a protein that is expressed in various tissues throughout the body. It is a key component of the immune system, making it an attractive drug target for researchers.

CXXC5 is a glycoprotein that consists of four subunits: 伪, 尾, 纬, and 未. It is found in various tissues, including the blood, spleen, thymus, heart, and kidneys. It is involved in the immune response by providing a surface for the activation and proliferation of immune cells.

One of the key functions of CXXC5 is its role in the activation of natural killer cells (NK cells). NK cells are a type of immune cell that play a crucial role in fighting off infections and cancer. They are able to recognize and destroy infected or abnormal cells without being confused by other immune cells.

CXXC5 has also been shown to play a role in the regulation of the immune response. It has been shown to be involved in the development and maintenance of tolerance, which is the ability of the immune system to distinguish between self and non-self and avoid attacking the body's own tissues.

CXXC5 is also involved in the regulation of inflammation. It has been shown to play a role in the regulation of inflammation and the immune response by controlling the activity of immune cells.

CXXC5 has also been shown to have potential as a drug target in various diseases, including cancer, cardiovascular disease, and autoimmune disorders.

One of the most promising potential drug targets for CXXC5 is its role in cancer. CXXC5 has been shown to be involved in the regulation of cancer cell growth and survival. It has been shown to play a role in the development of various types of cancer, including breast, lung, and ovarian cancer.

CXXC5 has also been shown to be involved in the regulation of angiogenesis, which is the process by which cancer cells grow and form blood vessels to supply them with oxygen and nutrients. This is a critical step in the development of cancer, and targeting CXXC5 may be a promising strategy for the treatment of cancer.

Another potential drug target for CXXC5 is its role in cardiovascular disease. CXXC5 has been shown to be involved in the regulation of blood pressure and cholesterol levels, which are critical factors in the development of cardiovascular disease.

CXXC5 has also been shown to be involved in the regulation of autoimmune disorders. These are a type of disease in which the immune system attacks the body's own tissues, leading to inflammation and pain.

In conclusion, CXXC5 is a protein that is involved in various aspects of the immune system. It has been shown to play a key role in the regulation of natural killer cells, the immune response, inflammation, and cancer cell growth. As a result, CXXC5 is an attractive drug target for the treatment of a variety of diseases, including cancer, cardiovascular disease, and autoimmune disorders.

Protein Name: CXXC Finger Protein 5

Functions: May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells (By similarity). Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis. Transcription factor. Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions (4% oxygen), as well as normoxia conditions (20% oxygen) (PubMed:23303788). May repress COX4I2 transactivation induced by CHCHD2 and RBPJ (PubMed:23303788). Binds preferentially to DNA containing cytidine-phosphate-guanosine (CpG) dinucleotides over CpH (H=A, T, and C), hemimethylated-CpG and hemimethylated-hydroxymethyl-CpG (PubMed:29276034)

The "CXXC5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CXXC5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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