Target Name: CXCL1
NCBI ID: G2919
Review Report on CXCL1 Target / Biomarker Content of Review Report on CXCL1 Target / Biomarker
CXCL1
Other Name(s): GROa | GRO1 oncogene (melanoma growth stimulating activity, alpha) | GROA_HUMAN | GRO1 | GRO-alpha(4-73) | MGSA | GRO-alpha(5-73) | neutrophil-activating protein 3 | Neutrophil-activating protein 3 | melanoma growth stimulating activity, alpha | CXCL1 variant 1 | GRO1 oncogene (melanoma growth-stimulating activity) | MGSA-a | C-X-C motif chemokine 1 | C-X-C motif chemokine ligand 1 | melanoma growth stimulatory activity alpha | Growth-regulated alpha protein | C-X-C motif chemokine ligand 1, transcript variant 1 | FSP | fibroblast secretory protein | GRO-alpha(6-73) | MGSA alpha | GRO-alpha(1-73) | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | NAP-3 | Melanoma growth stimulatory activity | SCYB1

CXCL1: A Potential Drug Target for Cellular Processes

CXCL1 (Transforming Growth Factor-beta 1) is a cytokine that plays a crucial role in the regulation of cellular processes, including cell adhesion, migration, and invasion. It is a member of the TGF-beta family, which includes several other cytokines that regulate cellular processes. CXCL1 is expressed in a variety of tissues and cells, including neural, epithelial, and hematopoietic cells.

CXCL1 has been shown to have a variety of functions, including promoting cell survival, activating cell signaling pathways, and regulating cellular processes that are important for tissue growth and development. It is involved in the development and maintenance of tissues and organs, including the nervous system, skin, and blood vessels.

One of the key functions of CXCL1 is its role in cell adhesion. CXCL1 is a strong adhesion molecule that can interact with several different cell types, including neural and epithelial cells. It is involved in the formation of tight junctions, which are critical for maintaining the integrity of tissues and organs. CXCL1 has been shown to be important for the development and maintenance of tissues that are barrier-bound, such as the skin and the gut lining.

CXCL1 is also involved in the regulation of cell signaling pathways. It is a potent activator of several different signaling pathways, including the TGF-beta pathway and the Wnt pathway. The TGF-beta pathway is a well-established pathway that is involved in the regulation of cellular processes that are important for tissue growth and development. CXCL1 has been shown to play a key role in the regulation of TGF-beta signaling by promoting the activity of the transcription factor, SMAD.

In addition to its role in cell signaling pathways, CXCL1 is also involved in the regulation of cellular processes that are important for tissue growth and development. It is involved in the regulation of cell proliferation, cell differentiation, and cell cycle progression. CXCL1 has been shown to play a key role in the regulation of cell proliferation by promoting the activity of the transcription factor, p21.

CXCL1 is also involved in the regulation of cellular processes that are important for immune function. It is a potent regulator of the immune response, and it has been shown to play a key role in the regulation of T cell development and function. CXCL1 has been shown to promote the activity of the transcription factor, NF-kappa-B, which is involved in the regulation of immune responses.

Given its variety of functions, CXCL1 is an attractive drug target for researchers who are interested in understanding the regulation of cellular processes. CXCL1 has been shown to play a key role in the regulation of a wide range of cellular processes, including cell adhesion, signaling pathways, cell proliferation, and immune function. As a result, CXCL1 is a potential drug target for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

In conclusion, CXCL1 is a cytokine that plays a crucial role in the regulation of cellular processes, including cell adhesion, signaling pathways, cell proliferation, and immune function. It is a potential drug target for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. Further research is needed to fully understand the regulation of cellular processes by CXCL1, and to develop effective therapies that target this protein.

Protein Name: C-X-C Motif Chemokine Ligand 1

Functions: Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity

The "CXCL1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CXCL1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

CXCL10 | CXCL11 | CXCL12 | CXCL13 | CXCL14 | CXCL16 | CXCL17 | CXCL2 | CXCL3 | CXCL5 | CXCL6 | CXCL8 | CXCL9 | CXCR1 | CXCR2 | CXCR2P1 | CXCR3 | CXCR4 | CXCR5 | CXCR6 | CXorf30 | CXorf38 | CXorf49 | CXorf49B | CXorf51A | CXorf51B | CXorf58 | CXorf65 | CXorf66 | CXXC1 | CXXC1P1 | CXXC4 | CXXC4-AS1 | CXXC5 | CYB561 | CYB561A3 | CYB561D1 | CYB561D2 | CYB5A | CYB5B | CYB5D1 | CYB5D2 | CYB5R1 | CYB5R2 | CYB5R3 | CYB5R4 | CYB5RL | CYBA | CYBB | CYBC1 | CYBRD1 | CYC1 | Cyclin | Cyclin A | Cyclin B | Cyclin D | Cyclin D2-CDK4 complex | Cyclin-dependent kinase | Cyclin-dependent kinase inhibitor | Cyclooxygenase (COX) | Cyclophilins | CYCS | CYCSP25 | CYCSP34 | CYCSP38 | CYCSP51 | CYCSP52 | CYCSP53 | CYCSP55 | CYFIP1 | CYFIP2 | CYGB | CYLC1 | CYLC2 | CYLD | CYLD-AS1 | CYMP | CYP11A1 | CYP11B1 | CYP11B2 | CYP17A1 | CYP19A1 | CYP1A1 | CYP1A2 | CYP1B1 | CYP1B1-AS1 | CYP20A1 | CYP21A1P | CYP21A2 | CYP24A1 | CYP26A1 | CYP26B1 | CYP26C1 | CYP27A1 | CYP27B1 | CYP27C1 | CYP2A13 | CYP2A6 | CYP2A7 | CYP2A7P1