Target Name: ZNF746
NCBI ID: G155061
Review Report on ZNF746 Target / Biomarker Content of Review Report on ZNF746 Target / Biomarker
ZNF746
Other Name(s): Zinc finger protein 746 (isoform 1) | Parkin-interacting sustrate | ZNF746 variant 2 | ZN746_HUMAN | Zinc finger protein 746 | Zinc finger protein 746 (isoform 2) | Zinc finger protein 746, transcript variant 2 | parkin-interacting sustrate | Parkin-interacting substrate | parkin-interacting substrate | Zinc finger protein 746, transcript variant 1 | FLJ31413 | PARIS | ZNF746 variant 1 | OTTHUMP00000213768 | zinc finger protein 746

ZNF746: A Potential Drug Target and Biomarker for Treatment of Neurodegenerative Disorders

Neurodegenerative disorders are a group of progressive diseases that affect the nervous system and can result in significant morbidity and mortality. These disorders include Alzheimer's disease, Parkinson's disease, Huntington's disease, and other forms of dementia. There is currently no cure for these conditions, and traditional therapies are limited in their ability to slow the progression of the disease and provide relief for symptoms. Therefore, the development of new treatments and biomarkers for neurodegenerative disorders is of great interest.

ZNF746: A Potential Drug Target and Biomarker

ZNF746 is a zinc finger protein 746 (isoform 1) that has been identified as a potential drug target and biomarker for the treatment of neurodegenerative disorders. ZNF746 is a transmembrane protein that is expressed in a variety of tissues, including brain, heart, and muscle. It plays a role in cell signaling and is involved in the development and maintenance of neural stem cells, as well as the regulation of neural circuitry.

The Potential Role of ZNF746 as a Drug Target

ZNF746 has been shown to play a role in a variety of neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. In these conditions, the levels of ZNF746 are often reduced, and its levels can be affected by various factors, such as age, gender, and environmental factors.

Studies have shown that ZNF746 levels are reduced in the brains of individuals with Alzheimer's disease, and that levels are also reduced in the brains of individuals with Parkinson's disease. Additionally, ZNF746 has been shown to be involved in the development of neurodegenerative disorders, and may be a potential drug target for these conditions.

The Potential Role of ZNF746 as a Biomarker

ZNF746 has also been shown to be a potential biomarker for the diagnosis and progression of neurodegenerative disorders. The levels of ZNF746 have been shown to be reduced in the brains of individuals with Alzheimer's disease and Parkinson's disease, and may be a potential biomarker for these conditions.

In addition, ZNF746 has been shown to be involved in the development of neurodegenerative disorders, and may be a potential biomarker for the early stages of these conditions. For example, studies have shown that ZNF746 levels are reduced in the brains of individuals with Huntington's disease, a neurodegenerative disorder that is characterized by the progressive loss of motor and cognitive function.

Conclusion

ZNF746 is a zinc finger protein 746 (isoform 1) that has been identified as a potential drug target and biomarker for the treatment of neurodegenerative disorders. The levels of ZNF746 are often reduced in the brains of individuals with neurodegenerative disorders, and its levels can be affected by various factors, such as age, gender, and environmental factors. ZNF746 has also been shown to play a role in the development and maintenance of neural stem cells, as well as the regulation of neural circuitry.

Further research is needed to fully understand the potential role of ZNF746 as a drug target and biomarker for the treatment of neurodegenerative disorders.

Protein Name: Zinc Finger Protein 746

Functions: Transcription repressor that specifically binds to the 5'-TATTTT[T/G]-3' consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death

The "ZNF746 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZNF746 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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