Discovering ZNF888: A Potent Drug Target and Biomarker (G388559)

Target Name: ZNF888

NCBI ID: G388559

ZNF888

Other Name(s): CTD-2331H12.6 | Zinc finger protein 888 | zinc finger protein 888 | ZN888_HUMAN

Discovering ZNF888: A Potent Drug Target and Biomarker

ZNF888 (CTD-2331H12.6) is a drug target and a potential biomarker for various diseases, including cancer. Its unique structure and function make it an attractive target for researchers to study.

ZNF888 is a small molecule that is derived from the gene ZNF2, which is a tumor suppressor gene that plays a crucial role in regulating cell growth and division. The ZNF2 gene was identified as a potential biomarker for various diseases, including cancer, due to its high expression levels in cancer cells compared to healthy cells.

One of the key features of ZNF888 is its nuclear localization, which is a hallmark of a protein that is involved in gene expression and cell signaling. ZNF888 has been shown to localize to the nuclear envelope, where it can interact with various transcription factors and other proteins involved in gene expression. This interaction between ZNF888 and these proteins suggests that it may play a role in regulating gene expression and cell signaling.

Another feature of ZNF888 is its ability to interact with DNA, which is a critical aspect of gene function. ZNF888 has been shown to bind to specific DNA sequences, which suggests that it may be involved in regulating gene expression and DNA replication. This interaction between ZNF888 and DNA also suggests that it may be a useful biomarker for diseases that involve disruptions in DNA replication, such as cancer.

In addition to its nuclear localization and interaction with DNA, ZNF888 has also been shown to have various other biological properties that make it an attractive drug target. For example, it has a relatively small size, which makes it easier to transport and manipulate in the body. ZNF888 also has a high degree of homogeneity, which suggests that it is stable and can be used as a single drug.

The potential applications of ZNF888 as a drug target are vast. In cancer, ZNF888 has been shown to be involved in various signaling pathways, including the regulation of cell division and the inhibition of apoptosis. This suggests that it may be an effective drug target for cancers that are characterized by uncontrolled cell division or disruptions in apoptosis.

In addition to its potential use as a cancer drug, ZNF888 has also been shown to be involved in other biological processes that are important for human health. For example, it has been shown to play a role in the regulation of stem cell proliferation, which is important for the development and maintenance of tissues and organs. ZNF888 may also be involved in the regulation of immune system function, which is important for protecting the body against infection and disease.

The discovery of ZNF888 as a potential drug target and biomarker has important implications for the development of new treatments for various diseases. By targeting ZNF888 with small molecules or other compounds, researchers may be able to inhibit its activity and prevent or reverse the development of diseases associated with its over-expression. This may lead to new treatments for diseases that are currently incurable or have limited effective options.

In conclusion, ZNF888 is a drug target and biomarker that has the potential to revolutionize the treatment of various diseases. Its unique structure and function, as well as its ability to interact with DNA and regulate cell division and apoptosis, make it an attractive target for small molecules and other compounds. As research continues to advance, the potential applications of ZNF888 as a drug and biomarker will become clearer, and its impact on human health will be felt for many years to come.

Protein Name: Zinc Finger Protein 888

Functions: May be involved in transcriptional regulation

The "ZNF888 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZNF888 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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