DSCAM: A Potential Drug Target and Biomarker (G1826)

Target Name: DSCAM

NCBI ID: G1826

DSCAM

DSCAM: A Potential Drug Target and Biomarker

DSCAM (Dietary supplement-concentrated artemisinin) is a dietary supplement derived from the ailingia sinensis plant, which has been shown to have potential health benefits. Artemisinin has been used in traditional Chinese medicine for centuries as a treatment for various diseases, including fever, malaria, and inflammation. In recent years, the scientific community has increasingly recognized the potential of artemisinin as a drug target and biomarker. This article will explore the potential of DSCAM as a drug target and biomarker.

DSCAM as a Drug Target

DSCAM is a flavonoid, which is a type of plant pigment that belongs to the group of polyphenolic compounds. Flavonoids have been shown to have a wide range of health benefits, including anti-inflammatory, anticoagulant, and antioxidant properties. Artemisinin specifically has been shown to have a unique combination of pharmacological properties that make it an attractive drug target.

One of the key features of DSCAM is its ability to selectively bind to nuclear receptors, which are responsible for regulating various cellular processes in the body. This binding allows DSCAM to modulate gene expression and promote the production of proteins that play a critical role in cell signaling pathways. One of the most promising aspects of DSCAM's potential as a drug target is its ability to selectively target the expression of genes involved in inflammation, oxidative stress, and cellular stress.

DSCAM has been shown to have a unique ability to modulate the expression of genes involved in inflammation and cellular stress. For example, studies have shown that DSCAM can downregulate the expression of genes involved in the production of pro-inflammatory cytokines, such as TNF-alpha, IL-1, and IL-6. This downregulation of pro-inflammatory cytokines has the potential to reduce inflammation and promote the resolution of inflammatory processes.

In addition to its ability to modulate inflammation, DSCAM has also been shown to have a unique ability to modulate cellular stress. Studies have shown that DSCAM can downregulate the expression of genes involved in the production of reactive oxygen species (ROS), which are highly reactive molecules that can damage cellular components and contribute to cellular stress. This downregulation of ROS production has the potential to reduce cellular stress and promote the resilience of cells under oxidative stress conditions.

DSCAM as a Biomarker

DSCAM has also been shown to have potential as a biomarker for a variety of diseases. For example, studies have shown that DSCAM can be used as a biomarker for the diagnosis and prognosis of certain types of cancer, including breast, ovarian, and prostate cancer. This is because DSCAM has been shown to have a unique ability to modulate the expression of genes involved in cancer cell growth and survival.

In addition to its potential as a cancer biomarker, DSCAM has also been shown to have potential as a biomarker for other diseases. For example, studies have shown that DSCAM can be used as a biomarker for the diagnosis and prognosis of cardiovascular disease, including heart failure, hypertension, and stroke. This is because DSCAM has been shown to have a unique ability to modulate the expression of genes involved in cardiovascular function and risk.

Conclusion

In conclusion, DSCAM has the potential to be a drug target and biomarker. Its unique ability to selectively bind to nuclear receptors and modulate the expression of genes involved in inflammation, oxidative stress, and cellular stress makes it an attractive target for drug development. Additionally, DSCAM's potential as a cancer and cardiovascular disease biomarker gives it a promising future in clinical

Protein Name: DS Cell Adhesion Molecule

Functions: Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Mediates within retinal amacrine and ganglion cell subtypes both isoneuronal self-avoidance for creating an orderly dendritic arborization and heteroneuronal self-avoidance to maintain the mosaic spacing between amacrine and ganglion cell bodies (PubMed:10925149). Receptor for netrin required for axon guidance independently of and in collaboration with the receptor DCC. Might also collaborate with UNC5C in NTN1-mediated axon repulsion independently of DCC (By similarity). In spinal cord development plays a role in guiding commissural axons projection and pathfinding across the ventral midline to reach the floor plate upon ligand binding (PubMed:18585357, PubMed:19196994). Mediates intracellular signaling by stimulating the activation of MAPK8 and MAP kinase p38 (PubMed:18585357, PubMed:19196994). Adhesion molecule that promotes lamina-specific synaptic connections in the retina: expressed in specific subsets of interneurons and retinal ganglion cells (RGCs) and promotes synaptic connectivity via homophilic interactions (By similarity)

The "DSCAM Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DSCAM comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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