Target Name: MECOM
NCBI ID: G2122
Review Report on MECOM Target / Biomarker Content of Review Report on MECOM Target / Biomarker
MECOM
Other Name(s): Histone-lysine N-methyltransferase MECOM (isoform e) | KMT8E | Zinc finger protein Evi1 | Histone-lysine N-methyltransferase MECOM (isoform d) | MDS1/EVI1 | MECOM_HUMAN | myelodysplasia syndrome-associated protein 1 | MDS1 and EVI1 complex locus protein | MECOM variant 3 | EVI1_1a | ecotropic virus integration site 1 protein homolog | MDS1-EVI1 | MDS1 and EVI1 complex locus, transcript variant 4 | EVI1_1c | MGC97004 | Ecotropic virus integration site 1 protein homolog | EVI1 | MDS1 | MDS1 and EVI1 complex locus protein MDS1 | MECOM variant 1 | MGC163392 | OTTHUMP00000213187 | MDS1 and EVI1 complex locus protein EVI1 (isoform c) | oncogene EVI1 | Oncogene EVI1 | Histone-lysine N-methyltransferase MECOM (isoform b) | MDS1 and EVI1 complex locus, transcript variant 7 | MECOM variant 2 | MECOM variant 6 | OTTHUMP00000213163 | MDS1 and EVI1 complex locus, transcript variant 1 | EVI-1 | zinc finger protein Evi1 | Histone-lysine N-methyltransferase MECOM (isoform a) | PR domain 3 | Histone-lysine N-methyltransferase MECOM | OTTHUMP00000213165 | MDS1 and EVI1 complex locus | MDS1 and EVI1 complex locus, transcript variant 6 | MDS1 and EVI1 complex locus protein EVI1 | Myelodysplasia syndrome 1 protein | MECOM variant 7 | MDS1 and EVI1 complex locus, transcript variant 5 | Ecotropic viral integration site 1 | OTTHUMP00000213164 | Histone-lysine N-methyltransferase MECOM (isoform c) | Myelodysplasia syndrome-associated protein 1 | RUSAT2 | MDS1 and EVI1 complex locus, transcript variant 3 | MECOM variant 5 | PRDM3 | MDS1 and EVI1 complex locus, transcript variant 2 | AML1-EVI-1 | OTTHUMP00000213192 | MECOM variant 4 | AML1-EVI-1 fusion protein

MECOM: A Potential Drug Target Or Biomarker for Various Diseases

MECOM (Histone-lysine N-methyltransferase MECOM (isoform e)) is a gene that has been identified as a potential drug target or biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. MECOM is a protein that is expressed in many different tissues and cells in the body, including the brain, spinal cord, and peripheral tissues. It is involved in the regulation of gene expression and has been shown to play a role in the development and progression of various diseases.

One of the unique features of MECOM is its ability to modify the histone code, which is the language of DNA. Histones are small, positively charged proteins that make up the nucleosome, which is the basic unit of DNA. They help to keep the chromosomes in a compact state and can also play a role in regulating gene expression. MECOM is specifically interested in modifying the lysine residue on the histone, which is a common modification that can alter the stability and localization of gene-coding regions.

MECOM has been shown to play a role in the regulation of gene expression in a wide variety of organisms, including humans. For example, studies have shown that MECOM is involved in the regulation of gene expression in cancer cells, and that it can inhibit the growth and survival of these cells. In addition, MECOM has been shown to be involved in the regulation of gene expression in neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

Another potential application of MECOM as a drug target is its role in the regulation of autoimmune disorders. MECOM has been shown to play a role in the regulation of immune cell function and has been implicated in the development of autoimmune diseases. For example, studies have shown that MECOM is involved in the regulation of the development of rheumatoid arthritis, a common autoimmune disorder. In addition, MECOM has also been shown to be involved in the regulation of the development of lupus, another autoimmune disorder.

In addition to its potential role as a drug target, MECOM has also been shown to have a number of potential applications as a biomarker. For example, MECOM has been shown to be a reliable biomarker for several types of cancer, including breast, ovarian, and colorectal cancer. In addition, MECOM has also been shown to be a reliable biomarker for neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

MECOM is also a potential drug target because of its ability to modify the histone code in a specific way. MECOM has been shown to add a positive charge to the lysine residue on the histone, which can alter its stability and localization. This modification has been shown to play a role in the regulation of gene expression and is thought to be a potential target for small molecules that can inhibit this modification.

In conclusion, MECOM is a gene that has been shown to play a number of roles in the regulation of gene expression and has potential as a drug target or biomarker for a wide variety of diseases. Further research is needed to fully understand the mechanisms of MECOM's role in these diseases and to develop effective treatments.

Protein Name: MDS1 And EVI1 Complex Locus

Functions: Functions as a transcriptional regulator binding to DNA sequences in the promoter region of target genes and regulating positively or negatively their expression. Oncogene which plays a role in development, cell proliferation and differentiation. May also play a role in apoptosis through regulation of the JNK and TGF-beta signaling. Involved in hematopoiesis

The "MECOM Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MECOM comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

MECOM-AS1 | MeCP1 histone deacetylase (HDAC) complex | MECP2 | MECR | MED1 | MED10 | MED11 | MED12 | MED12L | MED13 | MED13L | MED14 | MED14P1 | MED15 | MED15P8 | MED16 | MED17 | MED18 | MED19 | MED20 | MED21 | MED22 | MED23 | MED24 | MED25 | MED26 | MED27 | MED28 | MED29 | MED30 | MED31 | MED4 | MED4-AS1 | MED6 | MED7 | MED8 | MED9 | MEDAG | Mediator Complex | Mediator of RNA Polymerase II Transcription | MEF2A | MEF2B | MEF2C | MEF2C-AS1 | MEF2C-AS2 | MEF2D | MEFV | MEG3 | MEG8 | MEG9 | MEGF10 | MEGF11 | MEGF6 | MEGF8 | MEGF9 | MEI1 | MEI4 | MEIG1 | MEIKIN | MEIOB | MEIOC | MEIOSIN | MEIS1 | MEIS1-AS2 | MEIS1-AS3 | MEIS2 | MEIS3 | MEIS3P1 | MEIS3P2 | Melanin | Melanin-concentrating hormone (MCH) receptor | Melanocortin receptor | Melanoma-Associated Antigen | Melatonin receptor | MELK | MELTF | MELTF-AS1 | Membrane-Bound Protein Tyrosine Phosphatases (rPTPs) | Membrane-spanning 4-domains subfamily A member 4A | MEMO1 | MEMO1P1 | MEMO1P4 | MEMO1P5 | MEN1 | MEOX1 | MEOX2 | MEP1A | MEP1AP2 | MEP1AP4 | MEP1B | MEPCE | MEPE | MERTK | MESD | MESP1 | MESP2 | MEST | MESTIT1 | MESTP3 | MESTP4