Target Name: F2RL2
NCBI ID: G2151
Review Report on F2RL2 Target / Biomarker Content of Review Report on F2RL2 Target / Biomarker
F2RL2
Other Name(s): Thrombin receptor-like 2 | PAR3_HUMAN | Coagulation factor II receptor-like 2 (protease-actovated receptor 3) | F2RL2 variant 1 | thrombin receptor-like 2 | Coagulation factor II receptor-like 2 | Coagulation factor II thrombin receptor like 2, transcript variant 1 | protease-activated receptor 3 | coagulation factor II thrombin receptor like 2 | PAR3 | PAR-3 | Proteinase-activated receptor 3 | Proteinase-activated receptor 3 (isoform 1)

F2RL2: A Potential Drug Target Or Biomarker for Thrombin-Related Diseases

The F2RL2 gene, also known as thrombin receptor-like 2, is a gene that encodes a protein known as F2RL2. F2RL2 is a member of the F2RL family of proteins, which are characterized by the presence of a single transmembrane domain and a C-terminus that contains a leucine-rich repeat. These proteins are involved in various physiological processes, including blood clotting and aggregation.

Thrombin is a protein that plays a central role in blood clotting. It is a large protein that consists of multiple subunits, and it is involved in the formation of blood clots. Thrombin is activated by certain factors, including the presence of collagen and the F2RL2 protein.

The F2RL2 gene has been identified as a potential drug target or biomarker for thrombin-related diseases. This is because the F2RL2 protein has been shown to be involved in the formation of blood clots, which are a common symptom in thrombin-related diseases.

The F2RL2 protein is also a good candidate for a biomarker in thrombin-related diseases because it is highly expressed in various tissues and organs, including platelets, spleen, heart, liver, and brain. Additionally, the F2RL2 protein is well- conserved across various species, which indicates that it has a important role in the development and progression of thrombin-related diseases.

F2RL2 is also a potential drug target because it is involved in the regulation of cellular processes that are important for the development and progression of thrombin-related diseases. For example, studies have shown that the F2RL2 protein is involved in the regulation of platelet function, which is critical for the formation of blood clots. Additionally, the F2RL2 protein is involved in the regulation of angiogenesis, which is the process by which new blood vessels are formed.

The F2RL2 gene has also been shown to be involved in the regulation of cellular signaling pathways that are important for thrombin-related diseases. For example, studies have shown that the F2RL2 protein is involved in the regulation of the TGF-β pathway, which is a critical pathway involved in the development and progression of thrombin-related diseases.

In conclusion, the F2RL2 gene is a promising drug target or biomarker for thrombin-related diseases. The F2RL2 protein is involved in various physiological processes that are important for the development and progression of these diseases, including blood clotting and aggregation, platelet function, and cellular signaling pathways. Therefore, the F2RL2 protein is a good candidate for the development of new thrombin-related drugs or biomarkers.

Protein Name: Coagulation Factor II Thrombin Receptor Like 2

Functions: Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis

The "F2RL2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about F2RL2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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