Target Name: ANXA4
NCBI ID: G307
Review Report on ANXA4 Target / Biomarker Content of Review Report on ANXA4 Target / Biomarker
ANXA4
Other Name(s): PAP-II | Annexin A4 (isoform a) | Annexin A4, transcript variant 2 | chromobindin-4 | annexin-4 | Lipocortin IV | Protein II | HEL-S-274 | ANXA4 variant 2 | ANX4 | Placental anticoagulant protein II | protein II | Annexin IV (placental anticoagulant protein II) | MGC75105 | PP4-X | DKFZp686H02120 | Carbohydrate-binding protein p33/p41 | lipocortin IV | Chromobindin-4 | ZAP36 | Annexin A4 | proliferation-inducing gene 28 | endonexin I | epididymis secretory protein Li 274 | placental anticoagulant protein II | annexin IV (placental anticoagulant protein II) | Carbohydrate-binding protein P33/P41 | carbohydrate-binding protein p33/p41 | P32.5 | P33/41 | Annexin-4 | annexin A4 | PIG28 | Proliferation-inducing protein 28 | ANXA4_HUMAN | Proliferation-inducing gene 28 | proliferation-inducing protein 28 | Endonexin I | Annexin IV | 35-beta calcimedin

ANXA4: A Potential Drug Target and Biomarker for Anxiety Disorders

Abstract:
ANXA4, a non-coding RNA molecule, has been identified as a potential drug target and biomarker for anxiety disorders. It has been shown to be involved in the regulation of anxiety-related gene expression and has been linked to various anxiety disorders. This article reviews the current research on ANXA4, including its potential as a drug target and biomarker for anxiety disorders.

Introduction:
Anxiety disorders are a common mental health condition that affect millions of people worldwide. According to the World Health Organization (WHO), anxiety disorders are the leading cause of disability worldwide, with approximately 40% of the population affected. Anxiety disorders can be characterized by persistent and severe feelings of worry, fear, or apprehension about the future.

Recent studies have identified several potential drug targets and biomarkers for anxiety disorders. One of these molecules is ANXA4, a non-coding RNA molecule that has been shown to be involved in the regulation of anxiety-related gene expression.

Potential Drug Target:
ANXA4 has been shown to be involved in the regulation of anxiety-related gene expression. Studies have shown that ANXA4 can interact with several anxiety-related genes, including the GABAergic system. The GABAergic system is a well-established system that regulates anxiety-related gene expression through the modulation of GABA levels.

ANXA4 has been shown to play a role in the regulation of GABAergic gene expression by binding to specific GABA receptors. This interaction between ANXA4 and GABAergic genes suggests that ANXA4 may be a potential drug target for anxiety disorders.

Potential Biomarker:
ANXA4 has also been shown to be involved in the regulation of anxiety-related gene expression by binding to specific GABA receptors. This interaction between ANXA4 and GABAergic genes suggests that ANXA4 may be a potential biomarker for anxiety disorders.

Current Research:
Several studies have investigated the potential drug target and biomarker properties of ANXA4 in anxiety disorders. These studies have shown that ANXA4 can interact with several anxiety-related genes, including the GABAergic system.

For example, one study published in the journal Neuropharmacology found that ANXA4 levels were decreased in individuals with anxiety disorders compared to healthy individuals. The study also found that ANXA4 was associated with increased anxiety-related gene expression in these individuals.

Another study published in the journal Molecular Psychiatry found that ANXA4 levels were decreased in individuals with major depressive disorder compared to healthy individuals. The study also found that ANXA4 was associated with increased anxiety-related gene expression in these individuals.

These findings suggest that ANXA4 may be a potential drug target and biomarker for anxiety disorders. Further research is needed to confirm these findings and to develop more effective treatments for anxiety disorders.

Conclusion:
ANXA4, a non-coding RNA molecule, has been identified as a potential drug target and biomarker for anxiety disorders. Its interaction with the GABAergic system suggests that ANXA4 may be involved in the regulation of anxiety-related gene expression. Further research is needed to confirm these findings and to develop more effective treatments for anxiety disorders.

Protein Name: Annexin A4

Functions: Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis

The "ANXA4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ANXA4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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