ACSL6: A Potential Drug Target and Biomarker for Cancer (G23305)

Target Name: ACSL6

NCBI ID: G23305

ACSL6

ACSL6: A Potential Drug Target and Biomarker for Cancer

The ACSL6 gene (ACSL6) is a non-coding RNA molecule that has been identified as a potential drug target (1) and a biomarker for various diseases, including cancer. The ACSL6 gene is located on chromosome 6 and has been shown to play a role in various cellular processes, including cell adhesion, migration, and invasion.

Drug Target Potential

The ACSL6 gene has been identified as a potential drug target due to its involvement in several cellular processes that are associated with the development and progression of various diseases, including cancer. For example, studies have shown that overexpression of the ACSL6 gene is associated with the development of cancer cell lines. Additionally, the ACSL6 gene has been shown to play a role in the regulation of cell adhesion, which is a critical process for the development of cancer cell lines.

Biomarker Potential

The ACSL6 gene has also been identified as a potential biomarker for various diseases, including cancer. Studies have shown that the ACSL6 gene has been expressed in various tissues and fluids, including blood, saliva, and urine, which suggests that it may be a useful biomarker for cancer diagnosis and monitoring. Additionally, the ACSL6 gene has been shown to be downregulated in various types of cancer, which suggests that it may be a potential therapeutic target for cancer treatment.

Expression and regulation

The ACSL6 gene has been shown to be expressed in various tissues and organs, including the brain, heart, and pancreas. It has also been shown to be involved in the regulation of cell adhesion, as demonstrated by its role in the regulation of cell-cell adhesion in various tissues, including the regulation of tight junction in the brain.

The ACSL6 gene is also involved in the regulation of cell migration and invasion, as demonstrated by its role in the regulation of the migration of cancer cells in various tissues. Additionally, the ACSL6 gene has been shown to play a role in the regulation of various signaling pathways, including the PI3K/AKT signaling pathway.

Mutations in the ACSL6 gene have been identified as being associated with various diseases, including cancer. Studies have shown that mutations in the ACSL6 gene have been found in various types of cancer, including breast, ovarian, and colorectal cancer.

Conclusion

The ACSL6 gene has been identified as a potential drug target and biomarker for various diseases, including cancer. Its involvement in various cellular processes, including cell adhesion, migration, and invasion, as well as its involvement in the regulation of various signaling pathways, make it a promising target for drug development. Additionally, its expression in various tissues and its potential as a biomarker for cancer make it an attractive target for diagnostic and monitoring purposes. Further research is needed to fully understand the role of the ACSL6 gene in disease progression and to develop effective treatments.

Protein Name: Acyl-CoA Synthetase Long Chain Family Member 6

Functions: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:22633490, PubMed:24269233). Plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid

The "ACSL6 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ACSL6 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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