NXT1: A Potential Drug Target Or Biomarker (G29107)

Target Name: NXT1

NCBI ID: G29107

NXT1

NXT1: A Potential Drug Target Or Biomarker

NXT1 (NXT1_HUMAN), a protein that is expressed in various tissues and cells of the human body, has been identified as a potential drug target or biomarker. Its unique structure and various functions make it an attractive target for researchers to study.

NXT1 is a 21-kDa protein that is expressed in the brain, heart, liver, and kidneys. It is a member of the N-cadherin family, which is a well-known family of transmembrane proteins that are involved in cell-cell adhesion. NXT1 is known to play a role in the development and maintenance of various tissues and organs, including the brain.

One of the key functions of NXT1 is its role in the formation and maintenance of the blood-brain barrier (BBB). The BBB is a specialized barrier that separates the brain from the surrounding bloodstream, and it is designed to protect the brain from harmful substances that could cause damage. NXT1 is involved in the development and stability of the BBB, and studies have shown that it plays a critical role in this process.

In addition to its role in the BBB, NXT1 has also been shown to be involved in various other processes that are important for brain development and function. For example, NXT1 has been shown to be involved in the regulation of cell proliferation and differentiation, as well as in the formation of neural circuits. It has also been shown to play a role in the regulation of pain perception and neurotransmitter release.

Due to its various functions, NXT1 has been identified as a potential drug target or biomarker. Studies have shown that NXT1 can be targeted with small molecules, such as those that inhibit its activity in the BBB. Additionally, NXT1 has been shown to be involved in various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. Therefore, it has the potential to be used as a diagnostic or therapeutic target.

In conclusion, NXT1 (NXT1_HUMAN) is a protein that is expressed in various tissues and cells of the human body. Its unique structure and various functions make it an attractive target for researchers to study. The potential drug target or biomarker status of NXT1 makes it a promising target for future research.

Protein Name: Nuclear Transport Factor 2 Like Export Factor 1

Functions: Stimulator of protein export for NES-containing proteins (PubMed:10567585). Also plays a role in the nuclear export of U1 snRNA, tRNA, and mRNA (PubMed:10848583). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 (PubMed:19165146, PubMed:11259602)

The "NXT1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NXT1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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