ODF2: A Non-Coding RNA Molecule as A Potential Drug Target (G4957)

Target Name: ODF2

NCBI ID: G4957

ODF2

ODF2: A Non-Coding RNA Molecule as A Potential Drug Target

ODF2 (Open Reading Frame 2) is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for various diseases, including cancer. Its unique structure and function have made it an attractive target for researchers to study, and various studies have shown that ODF2 plays a significant role in the development and progression of these diseases.

The Open Reading Frame (ORF) is a region of DNA that is usually translated into a protein when a gene is expressed. ODF2 is a unique ORF that has a length of over 300 nucleotides and is highly conserved across various species. It is located at the start of the ORF and is involved in the regulation of gene expression.

One of the key features of ODF2 is its ability to interact with various transcription factors, including activator protein 1 (AP-1), which is a key transcription factor that regulates cell growth and differentiation. ODF2 has been shown to physically interact with AP-1 and to play a role in the regulation of AP-1 activity.

Additionally, ODF2 has been shown to be involved in the regulation of cell cycle progression. It has been shown to inhibit the G1 phase of the cell cycle and to promote the G2 phase, which is a critical phase for cell growth and division. This suggests that ODF2 may have potential as a drug target for diseases that are characterized by uncontrolled cell growth, such as cancer.

The role of ODF2 in cancer is still under investigation, but it is clear that ODF2 is involved in the regulation of cell growth and division. Several studies have shown that ODF2 is highly expressed in various types of cancer, including breast, lung, and ovarian cancer. Additionally, several studies have shown that ODF2 is involved in the regulation of cell apoptosis (programmed cell death), which is a natural mechanism that helps remove damaged or dysfunctional cells from the body.

In addition to its role in cell growth and apoptosis, ODF2 has also been shown to be involved in the regulation of cell signaling pathways. It has been shown to interact with various signaling molecules, including TGF-β1, which is a critical signaling molecule that regulates cell growth and differentiation.

The potential drug targets for ODF2 are vast, as it has been shown to be involved in the regulation of many different cellular processes. It is possible that ODF2 may be a drug target for diseases that are characterized by uncontrolled cellular growth, such as cancer, or for diseases that are characterized by abnormal cell signaling pathways, such as neurodegenerative diseases.

In conclusion, ODF2 is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for various diseases, including cancer. Its unique structure and function have made it an attractive target for researchers to study, and various studies have shown that ODF2 plays a significant role in the development and progression of these diseases. Further research is needed to fully understand the role of ODF2 in disease and to develop effective treatments.

Protein Name: Outer Dense Fiber Of Sperm Tails 2

Functions: Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly

The "ODF2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ODF2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets