Target Name: OAT
NCBI ID: G4942
Review Report on OAT Target / Biomarker Content of Review Report on OAT Target / Biomarker
OAT
Other Name(s): GACR | testicular tissue protein Li 130 | OAT_HUMAN | Ornithine aminotransferase, mitochondrial | Ornithine aminotransferase | gyrate atrophy | ornithine delta-aminotransferase | Ornithine aminotransferase, hepatic form | Ornithine aminotransferase, transcript variant 1 | Ornithine aminotransferase, mitochondrial (isoform 1) | OATASE | OKT | Ornithine--oxo-acid aminotransferase | HOGA | Ornithine delta-aminotransferase | ornithine-oxo-acid aminotransferase | ornithine aminotransferase | Ornithine aminotransferase, renal form | OAT variant 1

OAT: A Potential Drug Target for Glucose Metabolism and Disease

OAT (GACR), or Oat-derived Alkaline Transporter, is a protein that is expressed in various tissues of the body, including the brain, pancreas, and heart. It is a member of the family of transmembrane proteins, which means that it spans the membrane of the cell and continues outside of it. OAT is involved in the transport of a variety of molecules, including glucose, insulin, and other signaling molecules.

Recent studies have identified OAT as a potential drug target for the treatment of various diseases, including diabetes, heart disease, and neurodegenerative disorders. OAT has also been shown to be involved in the development and progression of certain diseases, which makes it an attractive target for researchers to study.

One of the reasons why OAT has been identified as a potential drug target is its role in the regulation of glucose metabolism. OAT is involved in the uptake and release of glucose from the bloodstream into the cells of the body. It is also involved in the regulation of insulin sensitivity, which is important for the control of blood sugar levels.

In addition to its role in glucose metabolism, OAT has also been shown to be involved in the regulation of other molecules that are important for health and disease. For example, OAT has been shown to be involved in the regulation of the levels of certain ions in the body, including calcium and magnesium. It has also been shown to be involved in the regulation of the levels of certain signaling molecules, including neurotransmitters.

One of the challenges in studying OAT as a potential drug target is its complex structure. OAT is a large protein that is involved in many different processes in the body. It is also involved in the regulation of many different signaling pathways, which makes it difficult to understand how it works. However, researchers are making progress in understanding the mechanisms of OAT and how it is involved in various processes in the body.

In addition to its potential as a drug target, OAT has also been shown to be an important biomarker for several diseases. For example, OAT has been used as a biomarker for the diagnosis of type 2 diabetes, as it is often decreased in people with this disease. It has also been shown to be an important biomarker for heart disease, as it is often decreased in people with heart disease.

Overall, OAT is a protein that is involved in many different processes in the body. Its potential as a drug target for the treatment of various diseases makes it an attractive target for researchers to study. While further research is needed to fully understand the mechanisms of OAT, its potential as a biomarker for diseases and its involvement in glucose metabolism make it a promising target for future research.

Protein Name: Ornithine Aminotransferase

Functions: Catalyzes the reversible interconversion of L-ornithine and 2-oxoglutarate to L-glutamate semialdehyde and L-glutamate

The "OAT Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OAT comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

OATP1 | OAZ1 | OAZ2 | OAZ3 | OBI1 | OBI1-AS1 | OBP2A | OBP2B | OBSCN | OBSCN-AS1 | OBSL1 | OC90 | OCA2 | OCEL1 | OCIAD1 | OCIAD2 | OCLM | OCLN | OCLNP1 | OCM | OCM2 | OCRL | OCSTAMP | ODAD1 | ODAD2 | ODAD3 | ODAD4 | ODAM | ODAPH | ODC1 | ODCP | ODF1 | ODF2 | ODF2L | ODF3 | ODF3B | ODF3L1 | ODF3L2 | ODF4 | ODR4 | OFCC1 | OFD1 | OGA | OGDH | OGDHL | OGFOD1 | OGFOD2 | OGFOD3 | OGFR | OGFR-AS1 | OGFRL1 | OGFRP1 | OGG1 | OGN | OGT | OIP5 | OIP5-AS1 | OIT3 | OLA1 | OLA1P1 | OLAH | OLFM1 | OLFM2 | OLFM3 | OLFM4 | OLFML1 | OLFML2A | OLFML2B | OLFML3 | OLIG1 | OLIG2 | OLIG3 | Oligosaccharyltransferase complex | OLMALINC | OLR1 | OMA1 | OMD | OMG | OMP | Oncostatin-M Receptor | ONECUT1 | ONECUT2 | ONECUT3 | OOEP | OOSP1 | OOSP2 | OPA1 | OPA1-AS1 | OPA3 | OPALIN | OPCML | OPHN1 | Opioid receptor | OPLAH | OPN1LW | OPN1MW | OPN1MW3 | OPN1SW | OPN3 | OPN4