Target Name: AOAH
NCBI ID: G313
Review Report on AOAH Target / Biomarker Content of Review Report on AOAH Target / Biomarker
AOAH
Other Name(s): AOAH variant 2 | Acyloxyacyl hydrolase (isoform 2) | Acyloxyacyl hydrolase (isoform 3) | AOAH variant 3 | acyloxyacyl hydrolase (neutrophil) | Acyloxyacyl hydrolase, transcript variant 2 | Acyloxyacyl hydrolase (isoform 1) | Acyloxyacyl hydrolase, transcript variant 3 | Acyloxyacyl hydrolase | Acyloxyacyl hydrolase, transcript variant 1 | Acyloxyacyl hydrolase large subunit | Acyloxyacyl hydrolase (neutrophil) | Acyloxyacyl hydrolase small subunit | AOAH_HUMAN | AOAH variant 1 | acyloxyacyl hydrolase

AOAH: A Drug Target / Disease Biomarker

AOAH (Alkylator-Oxidase activator) is a protein that is expressed in various tissues throughout the body. It is involved in the detoxification of xenobiotics, which are harmful substances that can cause disease when consumed. AOAH is also involved in the metabolism of drugs and other substances that are harmful to the body.

One of the things that makes AOAH an interesting drug target is its unique structure. AOAH is a transmembrane protein, which means that it spans the cell membrane and is involved in various processes that occur within the cell. This makes it difficult to target the protein directly, but it also means that the drug developers have a great deal of flexibility in terms of how they can design their drugs.

AOAH is also involved in a number of different cellular processes, which makes it an attractive target for drugs that are designed to modulate cellular processes. For example, some drugs that are used to treat cancer are designed to inhibit the activity of AOAH, which is thought to be a key factor in the development of cancer.

In addition to its potential as a drug target, AOAH is also a potential biomarker. The production of AOAH is regulated by a number of different genes, which makes it an attractive target for drugs that are designed to modulate gene expression. This could be useful for the development of diagnostic tests for AOAH-related diseases.

Overall, AOAH is a protein that is involved in a number of different cellular processes, which makes it an attractive target for drugs that are designed to modulate these processes. Its unique structure and the fact that it is expressed in various tissues throughout the body also make it an attractive target for drugs that are designed to treat a wide range of diseases.

Protein Name: Acyloxyacyl Hydrolase

Functions: Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides (PubMed:1883828, PubMed:8089145, PubMed:29343645). By breaking down LPS, terminates the host response to bacterial infection and prevents prolonged and damaging inflammatory responses (By similarity). In peritoneal macrophages, seems to be important for recovery from a state of immune tolerance following infection by Gram-negative bacteria (By similarity)

The "AOAH Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about AOAH comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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