Target Name: AP5Z1
NCBI ID: G9907
Review Report on AP5Z1 Target / Biomarker Content of Review Report on AP5Z1 Target / Biomarker
AP5Z1
Other Name(s): adaptor related protein complex 5 zeta 1 subunit | adaptor-related protein complex 5 zeta subunit | adaptor related protein complex 5 subunit zeta 1 | Adaptor-related protein complex 5 zeta subunit | AP-5 complex subunit zeta-1 (isoform 1) | AP5Z1 variant 1 | Protein KIAA0415 | AP5Z1_HUMAN | zeta | adapter-related protein complex 5 zeta subunit | Adaptor related protein complex 5 subunit zeta 1, transcript variant 1 | OTTHUMP00000200469 | SPG48 | zeta5 | Zeta5 | AP-5 complex subunit zeta-1 | KIAA0415

AP5Z1: A Potential Drug Target and Biomarker for Adaptor-Related Protein Complex 5 Zeta 1 Subunit

Introduction

Apoptosis, the process of natural cell death, is a critical mechanism that regulates cell growth and development. It is a tightly controlled process that helps maintain tissue homeostasis and prevent excessive cell proliferation. The adapter-related protein complex (ARPC) 5 zeta 1 subunit is a protein that plays a crucial role in the regulation of apoptosis. It is composed of several subunits that work together to facilitate the formation of the ARPC and its subcellular localization. However, the functions of the ARPC 5 zeta 1 subunit, including its role in cell survival and death, are not well understood.

In recent years, significant research has identified potential drug targets and biomarkers for the ARPC 5 zeta 1 subunit. One of these potential drug targets is AP5Z1, a protein that is known to interact with the ARPC 5 zeta 1 subunit. The interaction between AP5Z1 and the ARPC 5 zeta 1 subunit suggests that AP5Z1 may play a critical role in the regulation of apoptosis and may be a potential drug target.

The ARPC 5 zeta 1 subunit and its function in apoptosis

The ARPC 5 zeta 1 subunit is a protein that is composed of several subunits that include the protein itself, as well as smaller non-protein subunits that interact with the protein. The ARPC 5 zeta 1 subunit is primarily located in the cytoplasm and is involved in the regulation of various cellular processes, including cell adhesion, migration, and the formation of tissues such as blood vessels.

In apoptosis, the ARPC 5 zeta 1 subunit plays a crucial role in the regulation of cell death. Studies have shown that the ARPC 5 zeta 1 subunit is involved in the formation of the ARPC and its subcellular localization. It is also involved in the regulation of Apoptosis-related signaling pathways, including the production of reactive oxygen species (ROS) and the formation of the apoptotic body.

The functions of the ARPC 5 zeta 1 subunit in apoptosis are complex and still not fully understood. However, research has identified several key roles for the ARPC 5 zeta 1 subunit in cell death. For example, studies have shown that the ARPC 5 zeta 1 subunit plays a role in the production of ROS, which are reactive oxygen species that can damage cellular components and contribute to the development of apoptosis. Additionally, the ARPC 5 zeta 1 subunit is involved in the formation of the apoptotic body, which is the cellular debris that is produced during apoptosis.

The potential drug target of AP5Z1

The ARPC 5 zeta 1 subunit is a protein that has not yet been fully characterized, and research has identified several potential drug targets. One of these potential drug targets is AP5Z1, a protein that has been shown to interact with the ARPC 5 zeta 1 subunit . The interaction between AP5Z1 and the ARPC 5 zeta 1 subunit suggests that AP5Z1 may play a critical role in the regulation of apoptosis and may be a potential drug target.

AP5Z1 is a protein that is expressed in various tissues and cells, including brain, heart, and pancreatic cancer. It has been shown to interact with several other proteins, including the ARPC 5 zeta 1 subunit. The interaction between AP5Z1 and the ARPC 5 zeta 1 subunit suggests that AP5Z1 may play a critical role in the regulation of apoptosis and may be a potential drug target.

The potential benefits of targeting AP

Protein Name: Adaptor Related Protein Complex 5 Subunit Zeta 1

Functions: As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed:20613862 it is a putative helicase required for efficient homologous recombination DNA double-strand break repair

The "AP5Z1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about AP5Z1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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