Target Name: AP1S2
NCBI ID: G8905
Review Report on AP1S2 Target / Biomarker Content of Review Report on AP1S2 Target / Biomarker
AP1S2
Other Name(s): adaptor protein complex AP-1 sigma-1B subunit | DC22 | syndromic 5 | adaptor related protein complex 1 sigma 2 subunit | AP-1 complex subunit sigma-2 | AP1S2_HUMAN | Adapter-related protein complex 1 sigma-1B subunit | adaptor-related protein complex 1 subunit sigma-1B | Adaptor related protein complex 1 sigma 2 subunit | adaptor related protein complex 1 subunit sigma 2 | Adaptor related protein complex 1 subunit sigma 2, transcript variant 1 | mental retardation, X-linked, syndromic 5 | sigma1B-adaptin | MRXS21 | golgi adaptor HA1/AP1 adaptin sigma-1B subunit | adapter-related protein complex 1 sigma-1B subunit | Sigma 1B subunit of AP-1 clathrin | Sigma-adaptin 1B | MRXS5 | Adaptor-related protein complex 1 subunit sigma-1B | PGS | Golgi adaptor HA1/AP1 adaptin sigma-1B subunit | X-linked | Adaptor related protein complex 1 subunit sigma 2, transcript variant 2 | AP1S2 variant 1 | clathrin adaptor complex AP1 sigma 1B subunit | MRXSF | AP1S2 variant 2 | Pettigrew X-linked mental retardation syndrome | Adaptor protein complex AP-1 subunit sigma-1B | MRX59 | Clathrin assembly protein complex 1 sigma-1B small chain | Clathrin adaptor complex AP1 sigma 1B subunit | SIGMA1B | Adaptor protein complex AP-1 sigma-1B subunit | Sigma1B-adaptin | AP-1 complex subunit sigma-2 (isoform 1) | clathrin assembly protein complex 1 sigma-1B small chain | mental retardation | AP-1 complex subunit sigma-2 (isoform 2)

Understanding The Role of AP-1 Sigma-1B in Protein Translation Efficiency

The adapter protein complex (APC) AP-1 sigma-1B subunit is a protein that plays a crucial role in the regulation of protein translation in the cell. It is a subunit of the APC, which is a complex of proteins that work together to bring amino acids terminally to the ribosome, where they can be translated into proteins.

One of the APC subunits, AP-1 sigma-1B, is a protein that contains a unique folds structure that is highly conserved across different species. This conserved folds structure is important for the function of the protein, as it allows it to interact with other proteins and molecules in the cell.

One of the key functions of AP-1 sigma-1B is its role in the regulation of protein translation efficiency. This is important for the overall health and function of the cell, as efficient protein translation is essential for the production of proteins that are involved in many different cellular processes.

One of the ways that AP-1 sigma-1B contributes to the regulation of protein translation efficiency is through its ability to interact with specific proteins that are involved in the process of protein translation. This interaction between AP-1 sigma-1B and these other proteins helps to ensure that AP-1 sigma-1B is able to effectively regulate the translation of the correct proteins into the cell.

Another key function of AP-1 sigma-1B is its role in the regulation of the stability of the APC. The APC is a complex of proteins that work together to regulate the translation of amino acids into the cell. The stability of the APC is important for the efficient regulation of protein translation, as a stable APC is more likely to be able to effectively interact with other proteins and molecules in the cell.

In addition to its role in the regulation of protein translation efficiency, AP-1 sigma-1B is also involved in the regulation of the stability of the APC. This is important for the efficient regulation of protein translation, as a stable APC is more likely to be able to effectively interact with other proteins and molecules in the cell.

AP-1 sigma-1B is also a potential drug target in the future. The high conservation of its folds structure and its involvement in the regulation of protein translation efficiency make it an attractive target for drug development. Additionally, its role in the regulation of the stability of the APC also makes it a potential biomarker for tracking the development and progression of diseases.

In conclusion, AP-1 sigma-1B is a protein that plays a crucial role in the regulation of protein translation efficiency in the cell. Its unique folds structure and its involvement in the regulation of protein translation efficiency make it an attractive target for drug development and potential biomarker for tracking the development and progression of diseases. Further research is needed to fully understand its role in the regulation of protein translation efficiency and to develop effective drugs and biomarkers for it.

Protein Name: Adaptor Related Protein Complex 1 Subunit Sigma 2

Functions: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules

The "AP1S2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about AP1S2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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AP1S3 | AP2A1 | AP2A2 | AP2B1 | AP2M1 | AP2S1 | AP3B1 | AP3B2 | AP3D1 | AP3M1 | AP3M2 | AP3S1 | AP3S2 | AP4B1 | AP4B1-AS1 | AP4E1 | AP4M1 | AP4S1 | AP5B1 | AP5M1 | AP5S1 | AP5Z1 | APAF1 | APBA1 | APBA2 | APBA3 | APBB1 | APBB1IP | APBB2 | APBB3 | APC | APC2 | APCDD1 | APCDD1L | APCDD1L-DT | APCS | APEH | APELA | APEX1 | APEX2 | APH1A | APH1B | API5 | APIP | APLF | APLN | APLNR | APLP1 | APLP2 | APMAP | APOA1 | APOA1-AS | APOA2 | APOA4 | APOA5 | APOB | APOBEC1 | APOBEC2 | APOBEC3A | APOBEC3A_B | APOBEC3B | APOBEC3B-AS1 | APOBEC3C | APOBEC3D | APOBEC3F | APOBEC3G | APOBEC3H | APOBEC4 | APOBR | APOC1 | APOC1P1 | APOC2 | APOC3 | APOC4 | APOC4-APOC2 | APOD | APOE | APOF | APOH | APOL1 | APOL2 | APOL3 | APOL4 | APOL5 | APOL6 | APOLD1 | Apolipoprotein B mRNA editing complex | APOM | APOO | APOOL | APOOP2 | APOOP5 | APP | APPAT | APPBP2 | APPL1 | APPL2 | APRG1 | APRT | APTR