Target Name: TNFRSF9
NCBI ID: G3604
Review Report on TNFRSF9 Target / Biomarker Content of Review Report on TNFRSF9 Target / Biomarker
TNFRSF9
Other Name(s): T cell antigen ILA | 4-1BB | CDw137 | Interleukin-activated receptor | induced by lymphocyte activation (ILA) | Tumor necrosis factor receptor superfamily member 9 | homolog of mouse 4-1BB | ILA | TNF receptor superfamily member 9 | TNR9_HUMAN | interleukin-activated receptor, homolog of mouse Ly63 | 4-1BB ligand receptor | CD137 antigen | 41BB | T-cell antigen ILA | receptor protein 4-1BB | CD137 | T-cell antigen 4-1BB homolog

ILA: Key Regulator of T Cell Development and Function

TNFRSF9 (T cell antigen ILA), also known as interleukin-3 (IL-3), is a protein that is expressed in various tissues of the body, including the immune system. It is a key regulator of T cell development and function, and is involved in the regulation of cell proliferation, differentiation, and survival.

ILA is a type of cytokine that is expressed by T cells, which are a crucial part of the immune system. T cells are responsible for recognizing and responding to foreign substances in the body, and are a key part of the immune response. ILA plays a key role in this process, as it helps to stimulate the development and activation of T cells.

One of the key functions of ILA is its role in T cell development. ILA is a critical signaling molecule that helps to regulate the development of T cells from stem cells. When stem cells differentiate into T cells, ILA plays a key role in this process, as it helps to stimulate the growth and proliferation of the stem cells.

ILA is also involved in the regulation of T cell function. When T cells are activated, ILA is released and helps to stimulate the production of other cytokines, such as interferon and transforming growth factor (TGF-β). These cytokines help to regulate the growth, survival, and differentiation of T cells.

ILA is also involved in the regulation of cell death. When T cells are no longer needed, ILA is released and helps to stimulate the production ofprogrammed cell death (PD-1). PD-1 is a cytokine that helps to induce cell death, and is a key part of the immune response.

TNFRSF9 is also a potential drug target. The ability of ILA to regulate T cell development and function makes it an attractive target for drug development. There are currently several drugs that are being developed to treat various types of cancer, including T cell malignancies. These drugs work by targeting ILA and inhibiting its activity.

In addition to its potential as a drug target, ILA is also an attractive biomarker for cancer. The ability of ILA to regulate T cell development and function makes it an important marker for cancer. Researchers are currently using ILA as a biomarker to diagnose and monitor various types of cancer.

In conclusion, TNFRSF9 (T cell antigen ILA) is a protein that is expressed in various tissues of the body and plays a key role in the regulation of T cell development and function. It is a potential drug target and a valuable biomarker for cancer. Further research is needed to fully understand the role of ILA in the immune system and its potential as a therapeutic agent.

Protein Name: TNF Receptor Superfamily Member 9

Functions: Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation

The "TNFRSF9 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TNFRSF9 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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