Target Name: GJB7
NCBI ID: G375519
Review Report on GJB7 Target / Biomarker Content of Review Report on GJB7 Target / Biomarker
GJB7
Other Name(s): bA136M9.1 | Connexin25 | gap junction protein, beta 7, 25kDa | connexin-25 | Gap junction beta-7 protein | CXB7_HUMAN | gap junction protein beta 7 | CX25 | connexin25 | Connexin 25 | Connexin-25 | Cx25 | Gap junction protein beta 7

GJB7: Potential Drug Target and Biomarker for Cancer

GJB7 (bA136M9.1) is a protein that is expressed in various tissues of the body, including the brain, heart, kidneys, and intestines. It is a member of the GJB7 family, which is characterized by the presence of an extracellular domain containing a conserved nucleotide sequence that is involved in the formation of a dimeric complex with other proteins.

GJB7 is involved in many different cellular processes in the body, including cell signaling, inflammation, and immune response. It is a potent modulator of cell-cell adhesion, and has been shown to play a role in the development and progression of various diseases, including cancer.

One of the most promising aspects of GJB7 is its potential as a drug target. GJB7 has been shown to be highly expressed in many types of cancer, including breast, lung, and ovarian cancer. It is also involved in the regulation of cellular signaling pathways that are often disrupted in cancer, and has been shown to be a potent inhibitor of the angiogenic factors that drive cancer growth.

In addition to its potential as a drug target, GJB7 is also a potential biomarker for cancer. Its expression has been shown to be elevated in a variety of cancer samples, and its levels have been used as a biomarker to predict the outcomes of various types of cancer therapies. This makes GJB7 an attractive candidate for use as a diagnostic or predictive marker for cancer.

GJB7 is also involved in several other cellular processes that are important for maintaining tissue homeostasis. It is a regulator of the cytoskeleton, and has been shown to play a role in the regulation of cell migration and the formation of tissues such as the placenta and the liver. It is also involved in the regulation of inflammation, and has been shown to play a role in the immune response.

In conclusion, GJB7 is a protein that is highly expressed in a variety of tissues and is involved in a wide range of cellular processes that are important for maintaining tissue homeostasis. Its potential as a drug target and biomarker make it an attractive candidate for further study . Further research is needed to fully understand the role of GJB7 in various biological processes and to determine its potential as a therapeutic agent.

Protein Name: Gap Junction Protein Beta 7

Functions: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell

The "GJB7 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GJB7 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

GJC1 | GJC2 | GJC3 | GJD2 | GJD3 | GJD4 | GK | GK2 | GK3 | GK5 | GKAP1 | GKN1 | GKN2 | GKN3P | GLA | GLB1 | GLB1L | GLB1L2 | GLB1L3 | GLC1C | GLCCI1 | GLCCI1-DT | GLCE | GLDC | GLDN | GLE1 | GLG1 | GLI1 | GLI2 | GLI3 | GLI4 | GLIDR | GLIPR1 | GLIPR1L1 | GLIPR1L2 | GLIPR2 | GLIS1 | GLIS2 | GLIS3 | GLIS3-AS1 | GLMN | GLMP | GLO1 | GLOD4 | GLOD5 | GLP1R | GLP2R | GLRA1 | GLRA2 | GLRA3 | GLRA4 | GLRB | GLRX | GLRX2 | GLRX3 | GLRX3P2 | GLRX5 | GLS | GLS2 | GLT1D1 | GLT6D1 | GLT8D1 | GLT8D2 | GLTP | GLTPD2 | Glucagon-like peptide receptor (GLP-R) | Glucosidase | GLUD1 | GLUD1P2 | GLUD1P3 | GLUD2 | GLUL | GLULP2 | GLULP4 | Glutamate receptor | Glutamate Receptor Ionotropic | Glutamate Receptor Ionotropic AMPA Receptor | Glutamate Transporter | Glutaminase | Glutathione peroxidase | Glutathione S-Transferase (GST) | GLYAT | GLYATL1 | GLYATL1B | GLYATL2 | GLYATL3 | GLYCAM1 | Glycine receptor | Glycogen phosphorylase | Glycogen synthase | Glycogen synthase kinase 3 (GSK-3) | Glycoprotein hormone | Glycoprotein Hormone Receptor | GLYCTK | Glycylpeptide N-tetradecanoyltransferase | Glypican | GLYR1 | GM-CSF Receptor (GM-CSF-R) | GM1 ganglioside | GM2A