Unlocking the Potential of LOC400682: A Zinc Finger Protein 100-Like as a Drug Target and Biomarker
Unlocking the Potential of LOC400682: A Zinc Finger Protein 100-Like as a Drug Target and Biomarker
Introduction
Location 400682 (LOC400682) is a gene that encodes a protein known as zinc finger protein 100-like (ZNF100-like). ZNF100-like is a family of proteins that play a crucial role in various cellular processes, including gene regulation, DNA replication , and cell growth. This gene has been identified as a potential drug target and biomarker due to its unique structure and its involvement in various diseases, including cancer, neurodegenerative diseases, and developmental disorders.
The ZNF100-like Protein
ZNF100-like is a member of the ZNF family, which is characterized by the presence of a ZNF1 domain and multiple N-terminal and C-terminal fingers. This family of proteins is known for its ability to interact with various DNA-binding proteins, including transcription factors, thereby modulating gene expression.
LOC400682 encodes a protein with 199 amino acid residues, including a N-terminal ZNF1 domain, 21 N-terminal amino acids, and 14 C-terminal amino acids. The ZNF1 domain is a unique feature that consists of a specific sequence known as \" Conserved sequence list\" (conserved sequence), which is involved in the formation of a zinc ion-dependent ligand binding site.
Expression and Localization
LOC400682 is highly expressed in various tissues, including brain, heart, liver, and muscle. It is also expressed in various types of cancer, including breast, ovarian, and colorectal cancer. This protein has been shown to be involved in various cellular processes, including cell growth, apoptosis, and DNA replication.
In addition to its expression, LOC400682 has also been shown to localize to specific cellular structures. For instance, it has been shown to be located in the nuclei of various cell types, including cancer cells. This localization suggests that LOC400682 may play a role in the regulation of cellular processes that are specific to these cells.
Drug Target Potential
The unique structure of LOC400682, including its ZNF1 domain, makes it an attractive drug target. ZNF1 domain has been shown to be involved in various cellular processes, including gene regulation, DNA replication, and cell growth. Therefore, LOC400682 may be a useful drug target for various diseases, including cancer, neurodegenerative diseases, and developmental disorders.
One potential drug that targets LOC400682 is the small molecule inhibitor, Panglysidin A. Penremycin, a compound derived from sequoia trees, has been shown to inhibit the proliferation of a variety of cancer cells. Experimental results show that pontomycin can significantly inhibit the expression of LOC400682 and inhibit its cell growth.
Biomarker Potential
LOC400682 may also be used as a biomarker for various diseases, including cancer. The expression of LOC400682 has been shown to be involved in the regulation of cellular processes specific to cancer cells. Therefore, LOC400682 may be a useful biomarker for various types of cancer, including breast, ovarian, and colorectal cancer.
Conclusion
LOC400682 is a unique protein that encodes a zinc finger protein 100-like. Its structure and localization to specific cellular structures make it an attractive drug target and biomarker. The potential drug target for LOC400682 is the small molecule inhibitor,Panglysidin A ). Further studies are needed to fully understand the role of LOC400682 in various cellular processes and its potential as a drug target and biomarker.
Protein Name: Zinc Finger Protein 100-like
The "LOC400682 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC400682 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
LOC400692 | LOC400706 | LOC400707 | LOC400768 | LOC400940 | LOC401021 | LOC401052 | LOC401127 | LOC401261 | LOC401312 | LOC401324 | LOC401357 | LOC401410 | LOC401478 | LOC401480 | LOC401557 | LOC401589 | LOC401703 | LOC401913 | LOC402221 | LOC403312 | LOC407835 | LOC414300 | LOC439933 | LOC440157 | LOC440300 | LOC440311 | LOC440313 | LOC440700 | LOC440864 | LOC440895 | LOC440910 | LOC440982 | LOC441052 | LOC441081 | LOC441087 | LOC441179 | LOC441228 | LOC441239 | LOC441455 | LOC441666 | LOC441722 | LOC441956 | LOC442028 | LOC442497 | LOC497256 | LOC541473 | LOC550113 | LOC553139 | LOC554206 | LOC574080 | LOC606724 | LOC613266 | LOC642131 | LOC642361 | LOC642422 | LOC642502 | LOC642590 | LOC642677 | LOC642730 | LOC642846 | LOC642947 | LOC643201 | LOC643339 | LOC643406 | LOC643441 | LOC643454 | LOC643763 | LOC643855 | LOC643923 | LOC644006 | LOC644083 | LOC644086 | LOC644189 | LOC644215 | LOC644277 | LOC644525 | LOC644584 | LOC644634 | LOC644656 | LOC644662 | LOC644669 | LOC644893 | LOC644936 | LOC645086 | LOC645181 | LOC645188 | LOC645266 | LOC645468 | LOC645503 | LOC645967 | LOC646044 | LOC646214 | LOC646358 | LOC646471 | LOC646674 | LOC646736 | LOC646762 | LOC646813 | LOC646836
