Target Name: LOC645188
NCBI ID: G645188
Review Report on LOC645188 Target / Biomarker Content of Review Report on LOC645188 Target / Biomarker
LOC645188
Other Name(s): SPANX-L | uncharacterized LOC645188 | Uncharacterized LOC645188

LOC645188: A Protein Regulator of Cell Cycle Progression, Apoptosis and Inflammation

LOC645188 (SPANX-L), a protein located in the serine proteasome, is a key regulator of cellular processes that are essential for cell survival and growth. Discovered in 2014, LOC645188 has been shown to play a critical role in the regulation of cell cycle progression, apoptosis, and inflammation.

The serine proteasome is a complex protein network that plays a crucial role in the regulation of protein homeostasis, cell signaling, and cellular processes that are essential for cell survival and growth. The serine proteasome is composed of a highly conserved N-terminus and a variable C-terminus that contains multiple regulatory interactions with other proteins.

LOC645188 is a 21-kDa protein that is located in the N-terminus of the serine proteasome. It is composed of a unique fusion protein that consists of a 21-kDa catalytic domain and a 5.5-kDa transmembrane region. The catalytic domain of LOC645188 contains a unique ATP-binding site that is rare in proteins of its size.

Recent studies have shown that LOC645188 plays a critical role in the regulation of cell cycle progression, apoptosis, and inflammation. LOC645188 has been shown to regulate the assembly and disassembly of the serine proteasome, as well as the regulation of protein homeostasis.

In addition to its role in regulating the serine proteasome, LOC645188 has also been shown to play a critical role in the regulation of cell apoptosis. Apoptosis is a critical mechanism that helps cells eliminate themselves when they are no longer needed or when their environment is no longer supportive. LOC645188 has been shown to regulate the programmed cell death that is associated with apoptosis, as well as the regulation of cell cycle progression and the expression of pro-inflammatory genes.

LOC645188 has also been shown to play a critical role in the regulation of inflammation. Inflammation is a critical response of the immune system to harmful stimuli, and it can lead to tissue damage and chronic inflammatory diseases. LOC645188 has been shown to regulate the production of pro-inflammatory cytokines and to modulate the regulation of immune cell function.

In conclusion, LOC645188 is a protein that is located in the serine proteasome and has been shown to play a critical role in the regulation of cell cycle progression, apoptosis, and inflammation. Its unique structure and function make it an attractive drug target and a potential biomarker for a variety of diseases. Further research is needed to fully understand the role of LOC645188 in cellular processes and to develop effective therapies based on its unique properties.

Protein Name: Uncharacterized LOC645188

The "LOC645188 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC645188 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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