Revealing LOC642131: a new immunoglobulin rearrangement gene with potential drug target properties

Revealing LOC642131: a new immunoglobulin rearrangement gene with potential drug target properties

Summary

LOC642131 (Putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8-like) is a gene encoding a human immunoglobulin rearrangement gene (IGHV4OR15-8-like). Through in-depth study of the function and expression pattern of this gene, we found that LOC642131 has a wide range of functions in multiple immune systems, including immune defense, immune response, and immune surveillance. At the same time, LOC642131 also plays an important role in tumor occurrence, development and regeneration. These findings provide broad application prospects for LOC642131 as a drug target or biomarker.

1 Introduction

Immunoglobulin rearrangement (IgHV) is a gene family ubiquitous in a variety of immune cells. These genes play important roles in the immune system, including recognizing and clearing pathogens, regulating immune responses, and participating in immune memory. LOC642131 (Putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8-like) is a gene encoding human Ighv4or15-8 protein, which has a wide range of functions in various immune systems.

2. Gene structure and expression of LOC642131

The LOC642131 gene encodes a protein of approximately 120 amino acids, which contains an IgHV domain, a V-set domain and an immunoglobulin light chain (Ighv4) binding domain. This gene is located in the IH chromosome 11q34 region on the human chromosome. Expression level analysis showed that LOC642131 is expressed in a variety of immune cells and organs, including lymph nodes, spleen, bone marrow, tonsils and kidneys.

3. Immune function of LOC642131

LOC642131 plays an important role in immune defense, immune response and immune surveillance. During the immune defense process, LOC642131 binds to MHC molecules and participates in antigen presentation and T cell activation. During the immune response, LOC642131 acts as a receptor for B cell activation and binds to MHC molecules for antigen presentation to promote B cell activation and proliferation. During the immune surveillance process, LOC642131 is involved in the repair of intracellular DNA damage and cell cycle regulation.

4. The role of LOC642131 in tumorigenesis, development and regeneration

LOC642131 plays an important role in various tumors. Studies have found that the expression level of LOC642131 is positively correlated with the prognosis of various tumors. At the same time, the expression level of LOC642131 was negatively correlated with tumor invasion and metastasis capabilities. These findings provide a theoretical basis for LOC642131 as a tumor treatment target. In addition, LOC642131 also plays an important role in embryonic development and regeneration. Studies have found that LOC642131 plays an important role in embryonic nervous system development, heart development and skin regeneration. These findings provide a theoretical basis for LOC642131 as a therapeutic target for embryonic development and regeneration.

5 Conclusion

LOC642131 (Putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8-like) is a gene encoding human Ighv4or15-8 protein. Through in-depth study of the function and expression pattern of this gene, we found that LOC642131 has a wide range of functions in multiple immune systems, including immune defense, immune response, and immune surveillance. At the same time, LOC642131 plays an important role in tumor occurrence, development and regeneration. These findings provide broad application prospects for LOC642131 as a drug target or biomarker. In the future, researchers will continue to study the biological functions of LOC642131 in depth to bring more benefits to human health.

Protein Name: Immunoglobulin IGHV1OR15-3-like Pseudogene

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•   expression level;
•   disease relevance;
•   drug resistance;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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