LOC400706: A Potent Modulator of GPCR Signaling (G400706)
LOC400706: A Potent Modulator of GPCR Signaling
LOC400706 is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the G-protein-coupled receptor (GPCR) family, which is a large superfamily of transmembrane proteins that play a key role in cellular signaling.
LOC400706 is characterized by its unique structure, which consists of a long extracellular domain and a short intracellular domain. The extracellular domain of LOC400706 is composed of a single protein that is divided into two distinct regions: an N-terminal region and a C-terminal region. The N-terminal region is responsible for the protein's ability to interact with ligands, while the C-terminal region is involved in the protein's stability and functions as a scaffold.
LOC400706 is a potent modulator of cellular signaling pathways, including those involved in pain, inflammation, and neurodegeneration. Its functions are dependent on its ability to interact with specific GPCR ligands, which are often found in the intracellular signaling cascade.
One of the unique features of LOC400706 is its ability to modulate the activity of multiple GPCRs, making it a versatile drug target. Its widespread distribution in various tissues and its ability to interact with multiple classes of GPCR ligands make it an attractive candidate for targeting a wide range of cellular processes.
LOC400706 has also been shown to play a role in the regulation of pain perception. Studies have shown that LOC400706 is involved in the modulation of pain sensitivity in animals, and that its activity can be blocked by small molecules that specifically interact with its extracellular domain.
In addition to its potential role in pain regulation, LOC400706 has also been shown to be involved in the regulation of inflammation and neurodegeneration. Its functions in these processes are dependent on its ability to interact with specific GPCR ligands that are involved in inflammation and neurodegeneration.
The structure and function of LOC400706 make it an attractive candidate for targeting with small molecules. Studies have shown that LOC400706 is a good predictor of its activity, and that small molecules that interact with its extracellular domain have been shown to be effective in modulating its activity.
In conclusion, LOC400706 is a drug target (or biomarker) that has the potential to be a valuable tool for the development of new therapeutic approaches for a wide range of diseases. Its unique structure and function, as well as its ability to interact with multiple classes of GPCR ligands, make it an attractive candidate for targeting a wide range of cellular processes. Further research is needed to fully understand its mechanisms of action and its potential as a drug target.
Protein Name: Uncharacterized LOC400706
The "LOC400706 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC400706 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
LOC400707 | LOC400768 | LOC400940 | LOC401021 | LOC401052 | LOC401127 | LOC401261 | LOC401312 | LOC401324 | LOC401357 | LOC401410 | LOC401478 | LOC401480 | LOC401557 | LOC401589 | LOC401703 | LOC401913 | LOC402221 | LOC403312 | LOC407835 | LOC414300 | LOC439933 | LOC440157 | LOC440300 | LOC440311 | LOC440313 | LOC440700 | LOC440864 | LOC440895 | LOC440910 | LOC440982 | LOC441052 | LOC441081 | LOC441087 | LOC441179 | LOC441228 | LOC441239 | LOC441455 | LOC441666 | LOC441722 | LOC441956 | LOC442028 | LOC442497 | LOC497256 | LOC541473 | LOC550113 | LOC553139 | LOC554206 | LOC574080 | LOC606724 | LOC613266 | LOC642131 | LOC642361 | LOC642422 | LOC642502 | LOC642590 | LOC642677 | LOC642730 | LOC642846 | LOC642947 | LOC643201 | LOC643339 | LOC643406 | LOC643441 | LOC643454 | LOC643763 | LOC643855 | LOC643923 | LOC644006 | LOC644083 | LOC644086 | LOC644189 | LOC644215 | LOC644277 | LOC644525 | LOC644584 | LOC644634 | LOC644656 | LOC644662 | LOC644669 | LOC644893 | LOC644936 | LOC645086 | LOC645181 | LOC645188 | LOC645266 | LOC645468 | LOC645503 | LOC645967 | LOC646044 | LOC646214 | LOC646358 | LOC646471 | LOC646674 | LOC646736 | LOC646762 | LOC646813 | LOC646836 | LOC646853 | LOC646903
