Target Name: LOC441228
NCBI ID: G441228
Review Report on LOC441228 Target / Biomarker Content of Review Report on LOC441228 Target / Biomarker
LOC441228
Other Name(s): Exportin, tRNA (nuclear export receptor for tRNAs) pseudogene | exportin for tRNA pseudogene

LOC441228: A Potential Drug Target and Biomarker for Exportin, tRNA (Nuclear Export Receptor for tRNAs) Pseudogene

Abstract:

LOC441228 is a non-coding RNA molecule located within the nuclear import receptor for tRNAs (NOR9819), which is a subunit of the nuclear export receptor for tRNAs (TOR). The function of LOC441228 is not well understood, but its expression has been shown to be highly expressed in the invasiveness and tumor growth of multiple cancers. At the same time, research also shows that LOC441228 plays a key role in certain types of neurodegenerative diseases. These findings provide an important theoretical basis for studying LOC441228 as a drug target or biomarker.

1. Introduction

LOC441228 is a non-coding RNA molecule whose coding gene is located on human chromosome 16 (16p36.1). The name LOC441228 comes from its position in the human chromosome corresponding to its encoding gene. In cells, the main function of LOC441228 is to participate in the intranuclear transport process, responsible for transporting proteins and RNA in the nucleus to the cytoplasm.

In recent years, studies have found that LOC441228 plays an important role in various cancers. In addition, LOC441228 also shows a key role in neurodegenerative diseases. These findings provide important clues for studying the role of LOC441228.

2. Functions and functions of LOC441228

1. LOC441228 participates in the intranuclear transport process

LOC441228 is one of the important players in the intranuclear transport process. Studies have shown that LOC441228 binds to nuclear transport proteins to transfer materials between the nucleus and cytoplasm. In addition, LOC441228 can also interact with certain proteins, thereby participating in the modification and degradation process of intracellular proteins.

1. The role of LOC441228 in cancer

Research shows that LOC441228 plays an important role in various cancers. For example, studies have found that the expression level of LOC441228 is positively correlated with the aggressiveness and tumor growth of various cancers. In addition, LOC441228 can also inhibit apoptosis, thus counteracting its effect on promoting tumor growth to a certain extent.

1. The role of LOC441228 in neurodegenerative diseases

Recent research suggests that LOC441228 also plays a key role in neurodegenerative diseases. Studies have found that the expression level of LOC441228 is positively correlated with the incidence and severity of neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease. In addition, LOC441228 can also regulate the growth and apoptosis of nerve cells, thereby playing a certain role in neurodegenerative diseases.

3. Mechanism of action of LOC441228

1. LOC441228鈥檚 mechanism of action and protein interaction

One of the important reasons why LOC441228 works in cells is its interaction with proteins. Studies have shown that LOC441228 can interact with a variety of proteins and thus participate in the modification and degradation of intracellular proteins. These interactions may have important effects on the function of LOC441228.

1. The mechanism of action of LOC441228 binds to RNA

One of the important reasons why LOC441228 works in cells is its binding to RNA. Studies have shown that LOC441228 can interact with certain RNA molecules and thus participate in the intracellular RNA transport and modification process. These interactions may have important effects on the function of LOC441228.

4. Conclusion

LOC441228 is a non-coding RNA molecule with multiple functions in cells. These functions include involvement in intranuclear transport processes, a role in cancer, and a role in neurodegenerative diseases. With the deepening of research, LOC441228 is expected to become an important drug target or biological

Protein Name: Exportin For TRNA Pseudogene

The "LOC441228 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC441228 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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