Target Name: LOC646853
NCBI ID: G646853
Review Report on LOC646853 Target / Biomarker Content of Review Report on LOC646853 Target / Biomarker
LOC646853
Other Name(s): Non-histone chromosomal protein HMG-17 pseudogene | non-histone chromosomal protein HMG-17 pseudogene

LOC646853: A Potential Drug Target and Biomarker for Chromosomal Protein HMG-17

Introduction

Chromosomal proteins are essential entities that play a crucial role in the maintenance of cellular identity and function. Among the many chromatin proteins, histone proteins are among the most well-studied and have been implicated in numerous cellular processes. One of the histone proteins, HMG -17, has been extensively investigated for its role in various cellular processes, including cell growth, differentiation, and gene regulation. However, the functions of HMG-17 in these processes are not well understood, and there is an urgent need for new therapeutic targets.

LOC646853: A Potential Drug Target and Biomarker

The gene encoding LOC646853, also known as HMG-17, has been identified as a potential drug target and biomarker for various diseases. LOC646853 is a 21-kDa protein that is highly conserved across various species, including humans. It is localized to the N -terminus of the histone molecule and is involved in the formation of the histone nucleosome, which is the basic unit of chromatin.

Drug Target Potential

The drug targeting of LOC646853 is based on its unique structure and the various functions it is involved in. One of the key features of LOC646853 is its ability to interact with various drug molecules, including small molecules, peptides, and antibodies. This interactivity makes it a potential drug target for various diseases.

For instance, LOC646853 has been shown to interact with various small molecules, including inhibitors of the DNA-protein binding activity of histones. This interaction suggests that LOC646853 may play a role in the regulation of chromatin structure and gene expression. Therefore, small molecules that can modulate LOC646853 activity may be useful as therapeutic agents for various diseases, including cancer, neurodegenerative diseases, and developmental disorders.

Biomarker Potential

The other basis for the drug targeting of LOC646853 is its potential as a biomarker for various diseases. The functions of LOC646853 in the regulation of chromatin structure and gene expression are not well understood, but its potential role in the development and progression of diseases makes it an attractive biomarker for various diseases.

Studies have shown that LOC646853 is involved in various cellular processes that are associated with the development and progression of diseases, including cancer, neurodegenerative diseases, and developmental disorders. For instance, LOC646853 has been shown to be involved in the regulation of cell growth, apoptosis , and angiogenesis, which are important processes in the development of cancer.

Furthermore, LOC646853 has been shown to be involved in the regulation of gene expression and has been implicated in the development of neurodegenerative diseases. This suggests that LOC646853 may be a useful biomarker for assessing the risk and progression of neurodegenerative diseases.

Conclusion

In conclusion, LOC646853 is a potential drug target and biomarker for various diseases due to its unique structure and the various functions it is involved in. Its ability to interact with various drug molecules and its potential as a biomarker for the development and progression of diseases make it an attractive target for further investigation. Further studies are needed to fully understand the functions of LOC646853 and its potential as a therapeutic agent.

Protein Name: Non-histone Chromosomal Protein HMG-17 Pseudogene

The "LOC646853 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC646853 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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