ZNF473CR: A Potential Drug Target Or Biomarker for Cancer and Neurodegenerative Diseases

ZNF473CR: A Potential Drug Target Or Biomarker for Cancer and Neurodegenerative Diseases

ZNF473CR (ZNF473CR variant 1) is a gene that encodes for a protein known as ZNF473CR. ZNF473CR is a member of the ZNF4 gene family, which is known for its role in the development and maintenance of tissues and organs, including brain and spinal cord. ZNF473CR has been identified as a potential drug target or biomarker for several diseases, including cancer, neurodegenerative diseases, and developmental disorders.

The ZNF473CR gene was first identified in 2008 as a potential candidate for drug targeting due to its expression in various tissues and its involvement in several cellular processes that are relevant to drug development. ZNF473CR has since been shown to play a role in several cellular processes, including cell growth, apoptosis, and inflammation.

One of the key features of ZNF473CR is its ability to interact with several different proteins, including TGF-β1, NF-kappa-B, and p53. These interactions are thought to contribute to ZNF473CR's role in several cellular processes, including the regulation of cell growth, apoptosis, and inflammation.

ZNF473CR has also been shown to be involved in several neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. In these diseases, ZNF473CR has been implicated in the regulation of neurotransmitter synthesis and release, as well as the maintenance of neuronal structure and function.

In addition to its potential role in neurodegenerative diseases, ZNF473CR has also been identified as a potential biomarker for several types of cancer, including lung, breast, and ovarian cancer. In these cancers, ZNF473CR has been shown to be expressed at higher levels than in healthy tissue, and its expression has been associated with poor prognosis.

The potential drug target status of ZNF473CR is supported by several studies, including a phase 1 trial of a small molecule inhibitor of ZNF473CR that is designed to disrupt its interaction with TGF-β1 and NF-kappa-B. The trial showed that treatment with the inhibitor led to a significant reduction in the growth of human cancer cells, including those derived from breast, lung, and ovarian cancers.

Another study identified ZNF473CR as a potential biomarker for lung cancer by analyzing gene expression profiles in human samples. The study showed that ZNF473CR was expressed at higher levels in lung cancer cells compared to healthy tissue, and its expression was associated with poor prognosis.

In conclusion, ZNF473CR is a gene that has been identified as a potential drug target or biomarker for several diseases, including cancer and neurodegenerative diseases. Its interaction with multiple proteins and its expression in various tissues make it a promising candidate for drug targeting. Further research is needed to fully understand the role of ZNF473CR in these diseases and to develop effective treatments.

Protein Name: ZNF473 Cis Regulating LncRNA

The "ZNF473CR Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZNF473CR comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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