LOX (LYOX_HUMAN), A Potential Drug Target and Biomarker (G4015)

Target Name: LOX

NCBI ID: G4015

Content of Review Report on LOX Target / Biomarker

LOX

LOX (LYOX_HUMAN), A Potential Drug Target and Biomarker

LOX (LYOX_HUMAN) is a protein that is expressed in various tissues of the human body, including the lungs, heart, kidneys, and intestines.LOX has been identified as a potential drug target and biomarker in various diseases, including cancer, cardiovascular disease, and autoimmune disorders.

Potential Drug Target

LOX has been shown to play a role in several cellular processes that are associated with the development and progression of various diseases. For example, Lox has been shown to promote the growth and survival of cancer cells, and has been used as a potential target for anti-cancer drugs. Additionally, Lox has been shown to contribute to the development of cardiovascular disease, including heart failure and hypertension.

Potential Biomarker

LOX has also been identified as a potential biomarker for several diseases, including cancer, cardiovascular disease, and autoimmune disorders. For example, Lox has been shown to be elevated in the blood of patients with cancer, and has been used as a potential marker for disease progression. Additionally, Lox has been shown to be elevated in the urine of patients with cardiovascular disease, and has been used as a potential marker for disease severity.

LOX Interactions

LOX has been shown to interact with several other proteins, including TGF-β1, PDGF, and NF-kappa-B. These interactions may have implications for the regulation of cellular processes that are associated with the development and progression of diseases.

Conclusion

LOX (LYOX_HUMAN) is a protein that has been identified as a potential drug target and biomarker in several diseases. Further research is needed to fully understand the role of Lox in cellular processes that are associated with disease development and progression. Identification of Lox as a potential drug target and biomarker may lead to the development of new treatments for a variety of diseases.

Protein Name: Lysyl Oxidase

Functions: Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin (PubMed:26838787). Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture (By similarity)

The "LOX Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOX comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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