Target Name: MIR145
NCBI ID: G406937
Review Report on MIR145 Target / Biomarker Content of Review Report on MIR145 Target / Biomarker
MIR145
Other Name(s): miR-145 | hsa-miR-145-3p | miRNA145 | hsa-mir-145 | MicroRNA 145 | microRNA 145 | hsa-miR-145-5p | MIRN145

MIR145: A promising drug target and biomarker for cancer treatment

Introduction

MicroRNA-145 (miR-145) is a non-coding RNA molecule that plays a crucial role in various cellular processes. It is expressed in various tissues and is involved in the regulation of gene expression, cell growth, and differentiation. miR-145 has also been implicated in cancer progression and has been identified as a potential drug target in cancer treatment. In this article, we will explore the biology of miR-145 and its potential as a drug target and biomarker.

The biology of miR-145

MiR-145 is a non-coding RNA molecule that is expressed in various tissues, including muscle, heart, liver, and brain. It is characterized by a unique structure, consisting of a hairpin loop and a stem-loop, which allows it to interact with other RNA molecules. MiR-145 is involved in the regulation of gene expression by binding to specific target genes.

One of the well-established functions of miR-145 is its role in cell growth and proliferation. MiR-145 has been shown to play a negative role in cell growth and has been linked to the regulation of cell cycle progression. Additionally , miR-145 has been shown to be involved in the regulation of cell apoptosis, which is a critical mechanism that regulates cell death and has a significant impact on cancer progression.

MiR-145 has also been shown to play a role in the regulation of tissue repair and regeneration. During wound healing, miR-145 has been shown to be involved in the regulation of the cell proliferation and migration that occurs during the wound healing process ( 5).

MiR-145 as a drug target

MiR-145 has been identified as a potential drug target due to its involvement in various cellular processes that are associated with cancer progression. One of the potential mechanisms by which miR-145 can be targeted is its role in the regulation of cell apoptosis. Cancer regulation cells often have defective apoptosis, which allows them to continue to divide and promote tumor growth. By targeting miR-145, researchers have found that they can induce apoptosis in cancer cells, which can lead to a reduction in tumor growth.

Another potential mechanism by which miR-145 can be targeted is its role in the regulation of cell cycle progression. Cancer cells have aberrant cell cycles, which allows them to continue to divide and promote tumor growth. By targeting miR-145, researchers have found that they can inhibit cell cycle progression and induce apoptosis in cancer cells.

MiR-145 as a biomarker

MiR-145 has also been identified as a potential biomarker for cancer diagnosis and treatment. One of the reasons for its potential as a biomarker is its stability and persistence in various tissues, which allows it to be detectable even at low concentrations. Additionally, the expression of miR-145 is often affected by various cellular processes, such as cell growth, apoptosis, and tissue repair, which can be used as potential biomarkers for cancer diagnosis and treatment.

In addition to its potential as a biomarker, miR-145 has also been shown to be involved in the regulation of various cellular processes that are associated with cancer progression. For example, miR-145 has been shown to be involved in the regulation of angiogenesis. , which is the process by which new blood vessels are formed in the body. Additionally, miR-145 has

Protein Name: MicroRNA 145

The "MIR145 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR145 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

MIR1468 | MIR1469 | MIR146A | MIR146B | MIR1470 | MIR1471 | MIR147A | MIR147B | MIR148A | MIR148B | MIR149 | MIR150 | MIR151A | MIR151B | MIR152 | MIR153-1 | MIR153-2 | MIR1537 | MIR1538 | MIR1539 | MIR154 | MIR155 | MIR155HG | MIR1587 | MIR15A | MIR15B | MIR16-1 | MIR16-2 | MIR17 | MIR17HG | MIR181A1 | MIR181A1HG | MIR181A2 | MIR181A2HG | MIR181B1 | MIR181B2 | MIR181C | MIR181D | MIR182 | MIR1825 | MIR1827 | MIR183 | MIR184 | MIR185 | MIR186 | MIR187 | MIR188 | MIR18A | MIR18B | MIR1908 | MIR1909 | MIR190A | MIR190B | MIR191 | MIR1910 | MIR1911 | MIR1912 | MIR1913 | MIR1914 | MIR1915 | MIR1915HG | MIR192 | MIR193A | MIR193B | MIR193BHG | MIR194-1 | MIR194-2 | MIR194-2HG | MIR195 | MIR196A1 | MIR196A2 | MIR196B | MIR197 | MIR1972-1 | MIR1972-2 | MIR1973 | MIR1976 | MIR198 | MIR199A1 | MIR199A2 | MIR199B | MIR19A | MIR19B1 | MIR19B2 | MIR200A | MIR200B | MIR200C | MIR200CHG | MIR202 | MIR202HG | MIR203A | MIR203B | MIR204 | MIR205 | MIR2052 | MIR2052HG | MIR2053 | MIR2054 | MIR205HG | MIR206